# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1107471 | Functional | Antagonist activity at BLT1 receptor expressed in human HL60 cells assessed as inhibition of LTB4-stimulated calcium flux after 30 mins | 24 | ALA1158546 | cell-based format | Scientific Literature | ||
2. | ALA1107472 | Functional | Inhibition of LTB4-stimulated human neutrophils migration after 30 mins by using CyQuant GR fluorescent dye | Homo sapiens | 16 | ALA1158546 | cell-based format | Scientific Literature | |
3. | ALA1107476 | Physicochemical | Lipophilicity, log D of compound at pH 7.4 | 6 | ALA1158546 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA1107477 | ADME | Solubility of compound in small intestinal contents in the fed state at pH 5 | 6 | ALA1158546 | assay format | Scientific Literature | ||
5. | ALA1107478 | ADME | Solubility of compound in small intestinal contents in the fasted state at pH 6.5 | 6 | ALA1158546 | assay format | Scientific Literature | ||
6. | ALA1107479 | ADME | Clearance in rat hepatocytes after 3 hrs | Rattus norvegicus | 6 | ALA1158546 | cell-based format | Scientific Literature | |
7. | ALA1107480 | Binding | Inhibition of human ERG expressed in CHO cells assessed as reduction of current amplitude | Homo sapiens | 6 | ALA1158546 | cell-based format | Scientific Literature | |
8. | ALA1107481 | Binding | Inhibition of human ERG expressed in CHO cells at 3 uM assessed as reduction of current amplitude | Homo sapiens | 6 | ALA1158546 | cell-based format | Scientific Literature | |
9. | ALA1107482 | ADME | Inhibition of CYP1A2 by fluorescence method | 6 | ALA1158546 | single protein format | Scientific Literature | ||
10. | ALA1107483 | ADME | Inhibition of CYP2D6 fluorescence method | 6 | ALA1158546 | single protein format | Scientific Literature | ||
11. | ALA1107484 | ADME | Inhibition of CYP2C19 fluorescence method | 6 | ALA1158546 | single protein format | Scientific Literature | ||
12. | ALA1107485 | ADME | Inhibition of CYP3A4 fluorescence method | 6 | ALA1158546 | single protein format | Scientific Literature | ||
13. | ALA1107486 | ADME | Inhibition of CYP2C9 fluorescence method | 6 | ALA1158546 | single protein format | Scientific Literature | ||
14. | ALA1107487 | ADME | Inhibition of CYP2C9 by LC/MS method | 6 | ALA1158546 | single protein format | Scientific Literature | ||
15. | ALA1115522 | Toxicity | Hepatotoxicity in po dosed rat assessed as increase in total bilirubin level treated for 14 days measured | Rattus norvegicus | 5 | ALA1158546 | organism-based format | Scientific Literature |