# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1107435 | B | Displacement of FITC-conjugated BH3-Bak peptide from Vaccinia virus recombinant N1L expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay | Vaccinia virus | 12 | ALA1157820 | assay format | Scientific Literature | |
2. | ALA1108205 | B | Binding affinity to Vaccinia virus recombinant N1L expressed in Escherichia coli BL21 (DE3) assessed as protein melting temperature at 106 uM by differential scanning calorimetry | Vaccinia virus | 4 | ALA1157820 | assay format | Scientific Literature | |
3. | ALA1108209 | B | Binding affinity to Vaccinia virus recombinant N1L expressed in Escherichia coli BL21 (DE3) assessed as effect on enthalpy of protein unfolding at 106 uM by differential scanning calorimetry | Vaccinia virus | 4 | ALA1157820 | assay format | Scientific Literature | |
4. | ALA1108211 | B | Displacement of FITC-conjugated BH3-Bak peptide from 1 uM Vaccinia virus recombinant N1L expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay | Vaccinia virus | 12 | ALA1157820 | assay format | Scientific Literature | |
5. | ALA1108212 | B | Displacement of FITC-conjugated BH3-Bak peptide from 0.5 uM Vaccinia virus recombinant N1L expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay | Vaccinia virus | 10 | ALA1157820 | assay format | Scientific Literature | |
6. | ALA1108213 | F | Antiviral activity against GFP-expressing Vaccinia virus WR infected in african green monkey CV1 cells after 2.5 days by fluorescence assay | Vaccinia virus | 2 | ALA1157820 | organism-based format | Scientific Literature | |
7. | ALA1108214 | F | Antiviral activity against GFP-expressing Vaccinia virus WR infected in human HT1080 cells after 2.5 days by fluorescence assay | Vaccinia virus | 2 | ALA1157820 | organism-based format | Scientific Literature | |
8. | ALA1108215 | A | Cytotoxicity against african green monkey CV1 cells at >100 uM after 2.5 day by ATP lite assay | Chlorocebus aethiops | 3 | ALA1157820 | cell-based format | Scientific Literature | |
9. | ALA1108216 | A | Cytotoxicity against human HT1080 cells at >100 uM after 2.5 day by ATP lite assay | Homo sapiens | 3 | ALA1157820 | cell-based format | Scientific Literature | |
10. | ALA1108217 | A | Therapeutic index, ratio of TC50 for african green monkey CV1 cells to EC50 for GFP-expressing Vaccinia virus WR infected in african green monkey CV1 cells | 2 | ALA1157820 | cell-based format | Scientific Literature | ||
11. | ALA1108218 | A | Therapeutic index, ratio of TC50 for human HT1080 cells to EC50 for GFP-expressing Vaccinia virus WR infected in human HT1080 cells | 2 | ALA1157820 | cell-based format | Scientific Literature |