| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1107435 | B | Displacement of FITC-conjugated BH3-Bak peptide from Vaccinia virus recombinant N1L expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay | Vaccinia virus | 12 | ALA1157820 | assay format | Scientific Literature | |
| 2. | ALA1107436 | B | Destabilizing effect on Vaccinia virus recombinant N1L expressed in Escherichia coli BL21 (DE3) assessed as decrease in equilibrium constant of protein dimerization at 100 uM by analytical ultracentrifugation | Vaccinia virus | 2 | ALA1157820 | assay format | Scientific Literature | |
| 3. | ALA1107437 | B | Displacement of FITC-conjugated BH3-Bim peptide from Vaccinia virus N-terminal GST-fused F1L expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay | Vaccinia virus | 3 | ALA1157820 | assay format | Scientific Literature | |
| 4. | ALA1108205 | B | Binding affinity to Vaccinia virus recombinant N1L expressed in Escherichia coli BL21 (DE3) assessed as protein melting temperature at 106 uM by differential scanning calorimetry | Vaccinia virus | 4 | ALA1157820 | assay format | Scientific Literature | |
| 5. | ALA1108209 | B | Binding affinity to Vaccinia virus recombinant N1L expressed in Escherichia coli BL21 (DE3) assessed as effect on enthalpy of protein unfolding at 106 uM by differential scanning calorimetry | Vaccinia virus | 4 | ALA1157820 | assay format | Scientific Literature | |
| 6. | ALA1108211 | B | Displacement of FITC-conjugated BH3-Bak peptide from 1 uM Vaccinia virus recombinant N1L expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay | Vaccinia virus | 12 | ALA1157820 | assay format | Scientific Literature | |
| 7. | ALA1108212 | B | Displacement of FITC-conjugated BH3-Bak peptide from 0.5 uM Vaccinia virus recombinant N1L expressed in Escherichia coli BL21 (DE3) by fluorescence polarization assay | Vaccinia virus | 10 | ALA1157820 | assay format | Scientific Literature | |
| 8. | ALA1108213 | F | Antiviral activity against GFP-expressing Vaccinia virus WR infected in african green monkey CV1 cells after 2.5 days by fluorescence assay | Vaccinia virus | 2 | ALA1157820 | organism-based format | Scientific Literature | |
| 9. | ALA1108214 | F | Antiviral activity against GFP-expressing Vaccinia virus WR infected in human HT1080 cells after 2.5 days by fluorescence assay | Vaccinia virus | 2 | ALA1157820 | organism-based format | Scientific Literature | |
| 10. | ALA1108215 | A | Cytotoxicity against african green monkey CV1 cells at >100 uM after 2.5 day by ATP lite assay | Chlorocebus aethiops | 3 | ALA1157820 | cell-based format | Scientific Literature | |
| 11. | ALA1108216 | A | Cytotoxicity against human HT1080 cells at >100 uM after 2.5 day by ATP lite assay | Homo sapiens | 3 | ALA1157820 | cell-based format | Scientific Literature | |
| 12. | ALA1794553 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] | Homo sapiens | 58,172 | ALA1201862 | cell-based format | PubChem BioAssays | |
| 13. | ALA1794584 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] | 63,980 | ALA1201862 | assay format | PubChem BioAssays | ||
| 14. | ALA1963988 | F | PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex. (Class of assay: confirmatory) | 2,420 | ALA1201862 | assay format | PubChem BioAssays | ||
| 15. | ALA1963888 | F | PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex. (Class of assay: confirmatory) | 1,728 | ALA1201862 | assay format | PubChem BioAssays | ||
| 16. | ALA2114810 | F | PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) | Homo sapiens | 86,035 | ALA1201862 | assay format | PubChem BioAssays | |
| 17. | ALA2354211 | F | PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-IDH1KD cell line. (Class of assay: confirmatory) | 35,070 | ALA1201862 | cell-based format | PubChem BioAssays | ||
| 18. | ALA2354221 | F | PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT. (Class of assay: confirmatory) | 172,532 | ALA1201862 | assay format | PubChem BioAssays | ||
| 19. | ALA2354254 | F | PubChem BioAssay. qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT. (Class of assay: confirmatory) | 153,867 | ALA1201862 | assay format | PubChem BioAssays | ||
| 20. | ALA2354282 | F | PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) | 9,957 | ALA1201862 | assay format | PubChem BioAssays |
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