# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1110052 | Binding | Inhibition of sheep brain dynamin 1 by malachite green GTPase assay | Ovis aries | 24 | ALA1157798 | assay format | Scientific Literature | |
2. | ALA1110055 | Binding | Inhibition of recombinant dynamin 2 expressed in Sf9 cells by malachite green GTPase assay | 5 | ALA1157798 | cell-based format | Scientific Literature | ||
3. | ALA1110056 | Binding | Inhibition of dynamin 2-mediated receptor-induced endocytosis in human U2OS cells assessed as uptake of Tf-TxR dye after 30 mins by automated acquisition and analysis system | Homo sapiens | 5 | ALA1157798 | cell-based format | Scientific Literature | |
4. | ALA1113788 | Binding | Inhibition of dynamin 1-mediated synaptic vesicle endocytosis in Sprague-Dawley rat synaptosomes assessed as uptake of FM 4-64 dye after 30 mins by automated acquisition and analysis system | Rattus norvegicus | 5 | ALA1157798 | subcellular format | Scientific Literature | |
5. | ALA1113789 | ADME | Cytotoxicity against human U2OS cells assessed as change in cell morphology after 30 mins | Homo sapiens | 3 | ALA1157798 | cell-based format | Scientific Literature | |
6. | ALA1113790 | Binding | Uncompetitive inhibition of dynamin 1 from sheep brain by Lineweaver-Burke plot | Ovis aries | 1 | ALA1157798 | assay format | Scientific Literature | |
7. | ALA4421886 | Binding | Inhibition of full-length native sheep brain dynamin 1 assessed as reduction in PS liposomes-induced GTPase activity using 20 nM full-length dynamin 1 | Ovis aries | 5 | ALA4421721 | assay format | Patent Bioactivity Data | |
8. | ALA4421887 | Binding | Ring stabilizer activity at full-length native sheep brain dynamin 1 assessed as stimulation of GTPase activity in absence of PS liposomes using 200 nM full-length dynamin 1 | Ovis aries | 5 | ALA4421721 | assay format | Patent Bioactivity Data | |
9. | ALA4421894 | Binding | Ring stabilizer activity at full-length native sheep brain dynamin 1 assessed as stimulation of GTPase activity in absence of PS liposomes | Ovis aries | 7 | ALA4421721 | assay format | Patent Bioactivity Data | |
10. | ALA4421896 | Binding | Ring stabilizer activity at recombinant dynamin 1 dimeric GG2 form (unknown origin) assessed as stimulation of GTPase activity using 200 to 1000 nM full-length dynamin | Homo sapiens | 3 | ALA4421721 | single protein format | Patent Bioactivity Data |