#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA1119822	Binding	Displacement of [3H](S)-N-(biphenyl-2-yl)-1-(2-(1-methyl-1H-benzo[d]imidazol-2-ylthio)acetyl)pyrrolidine-2-carboxamide from human OX1R expressed in CHO cells after 3 hrs by scintillation counting	Homo sapiens	9	ALA1155457	cell-based format	Scientific Literature
2.	ALA1119823	Binding	Displacement of [3H]N-cyclobutyl-5-methyl-N-(2-(1-methyl-1H-benzo[d]imidazol-2-ylthio)ethyl)-2-(2H-1,2,3-triazol-2-yl)benzamide from human OX1R expressed in CHO cells after 20 hrs by scintillation counting	Homo sapiens	9	ALA1155457	cell-based format	Scientific Literature
3.	ALA1119824	Binding	Displacement of [3H](S)-N-(2-(1H-pyrrol-1-yl)phenyl)-1-(2-(1-methyl-1H-benzo[d]imidazol-2-ylthio)acetyl)pyrrolidine-2-carboxamide from human OX2R expressed in CHO cells after 3 hrs by scintillation counting	Homo sapiens	9	ALA1155457	cell-based format	Scientific Literature
4.	ALA1119825	Functional	Antagonist activity at human OX1R expressed in CHO cells assessed as inhibition of orexin-A-induced intracellular calcium mobilization after 5 mins by FLIPR assay	Homo sapiens	8	ALA1155457	cell-based format	Scientific Literature
5.	ALA1119826	Functional	Antagonist activity at human OX2R expressed in CHO cells assessed as inhibition of orexin-A-induced intracellular calcium mobilization after 5 mins by FLIPR assay	Homo sapiens	8	ALA1155457	cell-based format	Scientific Literature
6.	ALA1119833	ADME	Clearance in dog at 0.5 mg/kg, iv	Canis lupus familiaris	8	ALA1155457	organism-based format	Scientific Literature
7.	ALA1119838	ADME	Oral bioavailability in dog at 3 mg/kg	Canis lupus familiaris	8	ALA1155457	organism-based format	Scientific Literature
8.	ALA1119843	ADME	Oral bioavailability in rat at 10 mg/kg	Rattus norvegicus	2	ALA1155457	organism-based format	Scientific Literature
9.	ALA1119844	ADME	Clearance in rat at 10 mg/kg, iv	Rattus norvegicus	1	ALA1155457	organism-based format	Scientific Literature
10.	ALA1119845	ADME	Ratio of drug level in brain to plasma in rat at 0.25 to 1.5 mg/kg, iv after 30 mins	Rattus norvegicus	1	ALA1155457	organism-based format	Scientific Literature
11.	ALA1119846	ADME	Ratio of drug level in CSF to plasma in rat at 0.25 to 1.5 mg/kg, iv after 30 mins	Rattus norvegicus	1	ALA1155457	organism-based format	Scientific Literature
12.	ALA1118516	Physicochemical	Lipophilicity, log P of the compound		2	ALA1155457	small-molecule physicochemical format	Scientific Literature
13.	ALA1118517	Functional	Antiinsomnic activity in Sprague-Dawley rat assessed as decrease in active wake duration at 10 mg/kg/day, po 30 mg/kg/day	Rattus norvegicus	2	ALA1155457	organism-based format	Scientific Literature
14.	ALA1118518	Functional	Antiinsomnic activity in Sprague-Dawley rat assessed as increase in rapid-eye movement at 10 mg/kg/day, po measured with 3 to 4 hrs post last dose	Rattus norvegicus	2	ALA1155457	organism-based format	Scientific Literature
15.	ALA1118519	Functional	Antiinsomnic activity in Sprague-Dawley rat assessed as increase in delta sleep duration at 10 mg/kg/day, po measured with 3 to 4 hrs post last dose	Rattus norvegicus	2	ALA1155457	organism-based format	Scientific Literature
16.	ALA1118520	Functional	Antiinsomnic activity in Sprague-Dawley rat assessed as decrease in light sleep duration at 10 mg/kg/day, po measured with 3 to 4 hrs post last dose	Rattus norvegicus	2	ALA1155457	organism-based format	Scientific Literature
17.	ALA1118521	ADME	Drug level in Sprague-Dawley rat plasma at 10 mg/kg/day, po after 1 hr	Rattus norvegicus	1	ALA1155457	organism-based format	Scientific Literature
18.	ALA1118522	ADME	Drug level in Sprague-Dawley rat CSF at 10 mg/kg/day, po after 1 hr	Rattus norvegicus	1	ALA1155457	organism-based format	Scientific Literature
19.	ALA1118523	Toxicity	Idiosyncratic toxicity in human liver microsomes assessed GSH-derived reactive electrophilic adduct formation at 10 uM after 60 mins by UPLC/HRMS analysis relative to labetalol	Homo sapiens	6	ALA1155457	microsome format	Scientific Literature
20.	ALA1119093	ADME	Fraction unbound in rat plasma	Rattus norvegicus	1	ALA1155457	cell-free format	Scientific Literature