| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3562018 | Functional | PubChem BioAssay. Immunotoxin (SS1P) sensitization/mitigation study - treatment arm. (Class of assay: confirmatory) | 401 | ALA1201862 | assay format | PubChem BioAssays | ||
| 2. | ALA3562036 | Functional | PubChem BioAssay. Immunotoxin (HA22) sensitization/mitigation study - treatment arm (High Dose). (Class of assay: confirmatory) | 120 | ALA1201862 | assay format | PubChem BioAssays | ||
| 3. | ALA3591898 | Binding | Inhibition of human TNKS2 catalytic activity | Homo sapiens | 9 | ALA3588759 | single protein format | Scientific Literature | |
| 4. | ALA3591899 | Binding | Inhibition of human TNKS1 catalytic activity | Homo sapiens | 9 | ALA3588759 | single protein format | Scientific Literature | |
| 5. | ALA3830929 | Binding | Inhibition of TNKS-1 (unknown origin) using histone as substrate incubated for 30 mins by colorimetric assay | Homo sapiens | 31 | ALA3826913 | single protein format | Scientific Literature | |
| 6. | ALA3830930 | Binding | Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells preincubated for 2 hrs followed by substrate addition measured after 30 mins | Homo sapiens | 31 | ALA3826913 | cell-based format | Scientific Literature | |
| 7. | ALA3830931 | Binding | Inhibition of PARP-1 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assay | Homo sapiens | 31 | ALA3826913 | single protein format | Scientific Literature | |
| 8. | ALA3829133 | Binding | Inhibition of tankyrase-mediated Wnt signalling in mouse TLg2 cells assessed as percentage of cells above median GFP fluorescent intensity at 10 uM under N2B27 differentiating condition by flow cytometric analysis (Rvb = 50%) | Mus musculus | 8 | ALA3826913 | cell-based format | Scientific Literature | |
| 9. | ALA1119029 | Binding | Inhibition of TNKS2 | 1 | ALA1155445 | single protein format | Scientific Literature | ||
| 10. | ALA1119030 | Binding | Inhibition of TNKS1 | 1 | ALA1155445 | single protein format | Scientific Literature | ||
| 11. | ALA1119031 | Binding | Binding affinity to TNKS2 | 1 | ALA1155445 | single protein format | Scientific Literature | ||
| 12. | ALA1119032 | Binding | Binding affinity to TNKS1 | 1 | ALA1155445 | single protein format | Scientific Literature | ||
| 13. | ALA1119033 | Binding | Selectivity for TNKS2 over PARP1 | 1 | ALA1155445 | assay format | Scientific Literature | ||
| 14. | ALA1119034 | Binding | Selectivity for TNKS1 over PARP1 | 1 | ALA1155445 | assay format | Scientific Literature | ||
| 15. | ALA1119035 | Binding | Selectivity for TNKS2 over PARP2 | 1 | ALA1155445 | assay format | Scientific Literature | ||
| 16. | ALA1119036 | Binding | Selectivity for TNKS1 over PARP2 | 1 | ALA1155445 | assay format | Scientific Literature | ||
| 17. | ALA1119037 | Binding | Binding affinity to full-length human recombinant TNSK2 expressed in Escherichia coli by isothermal titration calorimetry | Homo sapiens | 1 | ALA1155445 | assay format | Scientific Literature | |
| 18. | ALA1119038 | Binding | Binding affinity to human recombinant TNSK1 expressed in Escherichia coli by isothermal titration calorimetry | Homo sapiens | 1 | ALA1155445 | assay format | Scientific Literature | |
| 19. | ALA1119039 | Binding | Binding affinity to PARP1 by isothermal titration calorimetry | 1 | ALA1155445 | single protein format | Scientific Literature | ||
| 20. | ALA3381966 | Binding | Inhibition of GST-tagged human recombinant TNKS1 at 1 uM incubated for 1 hr using NAD+, biotinylated NAD+ and activated DNA by luminescence based assay | Homo sapiens | 19 | ALA3351316 | single protein format | Scientific Literature |
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