# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA781610 | F | Hypolipidemic activity was assessed by measuring alpha-cholesterol in Sprague-Dawley male rats at 50 mg/kg | Rattus norvegicus | 15 | ALA1122536 | organism-based format | Scientific Literature | |
2. | ALA779406 | F | Hypolipidemic activity was assessed by measuring cholesterol in Sprague-Dawley male rats at 50 mg/kg | Rattus norvegicus | 15 | ALA1122536 | organism-based format | Scientific Literature | |
3. | ALA786030 | A | Evaluated for the dose that causes 50 % lethality in Sprague-Dawley male rats | Rattus norvegicus | 15 | ALA1122536 | organism-based format | Scientific Literature | |
4. | ALA795605 | F | Hypolipidemic activity was assessed by measuring triglycerides in Sprague-Dawley male rats at 50 mg/kg | Rattus norvegicus | 15 | ALA1122536 | organism-based format | Scientific Literature | |
5. | ALA4414331 | B | Activation of human Gal4-fused RXRalpha LBD transfected in HEK293T after 14 to 16 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 23 | ALA4411340 | assay format | Scientific Literature | |
6. | ALA4414332 | B | Activation of human Gal4-fused RXRbeta LBD transfected in HEK293T after 14 to 16 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 23 | ALA4411340 | assay format | Scientific Literature | |
7. | ALA4414333 | B | Activation of human Gal4-fused RXRgamma LBD transfected in HEK293T after 14 to 16 hrs by dual-glo luciferase reporter gene assay | Homo sapiens | 22 | ALA4411340 | assay format | Scientific Literature | |
8. | ALA4414334 | B | Activation of human Gal4-fused RXRalpha LBD transfected in HEK293T at 1 uM after 14 to 16 hrs by dual-glo luciferase reporter gene assay relative to bexarotene | Homo sapiens | 26 | ALA4411340 | assay format | Scientific Literature | |
9. | ALA4414335 | B | Activation of human Gal4-fused RXRbeta LBD transfected in HEK293T at 1 uM after 14 to 16 hrs by dual-glo luciferase reporter gene assay relative to bexarotene | Homo sapiens | 26 | ALA4411340 | assay format | Scientific Literature | |
10. | ALA4414336 | B | Activation of human Gal4-fused RXRgamma LBD transfected in HEK293T at 1 uM after 14 to 16 hrs by dual-glo luciferase reporter gene assay relative to bexarotene | Homo sapiens | 25 | ALA4411340 | assay format | Scientific Literature | |
11. | ALA4414337 | B | Activation of human Gal4-fused PPARalpha LBD transfected in HEK293T at 1 uM after 14 to 16 hrs by dual-glo luciferase reporter gene assay relative to GW7647 | Homo sapiens | 25 | ALA4411340 | assay format | Scientific Literature | |
12. | ALA4414339 | B | Activation of human Gal4-fused PPARgamma LBD transfected in HEK293T at 1 uM after 14 to 16 hrs by dual-glo luciferase reporter gene assay relative to rosiglitazone | Homo sapiens | 25 | ALA4411340 | assay format | Scientific Literature | |
13. | ALA4414341 | B | Activation of human Gal4-fused PPARdelta LBD transfected in HEK293T at 1 uM after 14 to 16 hrs by dual-glo luciferase reporter gene assay relative to L165,041 | Homo sapiens | 17 | ALA4411340 | assay format | Scientific Literature | |
14. | ALA4414344 | A | Cytotoxicity against human HepG2 cells up to 50 uM after 48 hrs by WST1 assay | Homo sapiens | 27 | ALA4411340 | cell-based format | Scientific Literature |