# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1120299 | B | Activation of human PKM2 assessed as ATP product formation after 1 hr by luminescent pyruvate kinase-luciferase coupled assay | Homo sapiens | 46 | single protein format | Scientific Literature | ||
2. | ALA1120300 | B | Maximum activation of human PKM2 assessed as ATP product formation at 57 uM after 1 hr by luminescent pyruvate kinase-luciferase coupled assay relative to fructose-1,6-bis-phosphate | Homo sapiens | 46 | single protein format | Scientific Literature | ||
3. | ALA1120301 | P | Aqueous solubility in DMSO at pH 7.4 by quantitative nitrogen detection assay | 5 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA1120304 | B | Activation of PKM1 assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay | 46 | single protein format | Scientific Literature | |||
5. | ALA1120305 | B | Activation of PKL assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay | 46 | single protein format | Scientific Literature | |||
6. | ALA1120306 | B | Activation of PKR assessed as ATP product formation by luminescent pyruvate kinase-luciferase coupled assay | 46 | single protein format | Scientific Literature | |||
7. | ALA1120307 | B | Activation of PKM1 assessed as ATP product formation by luminescent pyruvate kinase-luciferase coupled assay | 46 | single protein format | Scientific Literature | |||
8. | ALA1120308 | B | Activation of PKR assessed as pyruvate formation by fluorescent pyruvate kinase-lactate dehydrogenase coupled assay | 46 | single protein format | Scientific Literature | |||
9. | ALA1120309 | B | Activation of PKL assessed as ATP product formation by luminescent pyruvate kinase-luciferase coupled assay | 46 | single protein format | Scientific Literature | |||
10. | ALA1613907 | F | PUBCHEM_BIOASSAY: Secondary assay for Activators of Human Pyruvate Kinase M2 isoform. (Class of assay: confirmatory) [Related pubchem assays: 1634, 1631 ] | Homo sapiens | 145 | assay format | PubChem BioAssays | ||
11. | ALA1613911 | F | PUBCHEM_BIOASSAY: Secondary LDH Assay for Activators of Human Reticulocyte Pyruvate Kinase: for Probe SAR. (Class of assay: confirmatory) [Related pubchem assays: 2095, 1631 ] | Homo sapiens | 24 | assay format | PubChem BioAssays | ||
12. | ALA1613854 | F | PUBCHEM_BIOASSAY: Secondary LDH Assay for Activators of Human Pyruvate Kinase M2 isoform: for Probe SAR. (Class of assay: confirmatory) | 70 | assay format | PubChem BioAssays | |||
13. | ALA1613920 | F | PUBCHEM_BIOASSAY: Confirmation Assay for Inhibitors of Leishmania Mexicana Pyruvate Kinase (LmPK): for Probe SAR. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1379, AID1721, AID2266] | Leishmania mexicana mexicana | 75 | assay format | PubChem BioAssays | ||
14. | ALA1613982 | F | PUBCHEM_BIOASSAY: Confirmation Concentration-Response Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase: for Probe SAR. (Class of assay: confirmatory) | 124 | assay format | PubChem BioAssays |