# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1120488 | Binding | Displacement [3H]Arg human recombinant Vasopressin V1a receptor | Homo sapiens | 57 | ALA1155536 | single protein format | Scientific Literature | |
2. | ALA1120489 | Binding | Displacement [3H]Arg human recombinant Vasopressin V2 receptor | Homo sapiens | 57 | ALA1155536 | single protein format | Scientific Literature | |
3. | ALA1120490 | Binding | Selectivity ratio of Ki for human Vasopressin V1a receptor to Ki for human Vasopressin V2 receptor | Homo sapiens | 42 | ALA1155536 | assay format | Scientific Literature | |
4. | ALA1120491 | Functional | Antagonist activity at human Vasopressin V1a receptor assessed as inhibition of intracellular calcium mobilization by FLIPR assay | Homo sapiens | 2 | ALA1155536 | cell-based format | Scientific Literature | |
5. | ALA1120492 | Functional | Antagonist activity at human Vasopressin 2 receptor assessed as inhibition of intracellular cAMP accumulation | Homo sapiens | 2 | ALA1155536 | cell-based format | Scientific Literature | |
6. | ALA1120493 | Binding | Selectivity ratio of IC50 for human Vasopressin V1a receptor to IC50 for human Vasopressin V2 receptor | Homo sapiens | 2 | ALA1155536 | assay format | Scientific Literature | |
7. | ALA1120494 | ADME | Half life in human liver microsome at 1 uM | Homo sapiens | 2 | ALA1155536 | microsome format | Scientific Literature | |
8. | ALA1120495 | ADME | Half life in mouse liver microsome at 1 uM | Mus musculus | 2 | ALA1155536 | microsome format | Scientific Literature | |
9. | ALA1120496 | Physicochemical | Solubility of the compound | 2 | ALA1155536 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA1120498 | ADME | Inhibition of CYP2D6 at 3 uM | 2 | ALA1155536 | single protein format | Scientific Literature | ||
11. | ALA1120499 | ADME | Inhibition of CYP2C9 at 3 uM | 2 | ALA1155536 | single protein format | Scientific Literature |