# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1118346 | Functional | Antitrypanosomal activity against Trypanosoma brucei brucei 427 bloodstream form after 72 hrs by LILIT method | Trypanosoma brucei brucei | 5 | ALA1158635 | organism-based format | Scientific Literature | |
2. | ALA1118347 | ADME | Cytotoxicity against human MRC5 cells after 72 hrs by Alamar blue staining | Homo sapiens | 5 | ALA1158635 | cell-based format | Scientific Literature | |
3. | ALA1118348 | Binding | Inhibition of rabbit muscle GAPDH | Oryctolagus cuniculus | 2 | ALA1158635 | single protein format | Scientific Literature | |
4. | ALA1118350 | Binding | Inhibition of Trypanosoma brucei GAPDH expressed in Escherichia coli | Trypanosoma brucei | 3 | ALA1158635 | assay format | Scientific Literature | |
5. | ALA1118353 | Binding | Selectivity ratio of IC50 for rabbit muscle GAPDH to IC50 for Trypanosoma brucei GAPDH | 2 | ALA1158635 | assay format | Scientific Literature | ||
6. | ALA1118357 | Binding | Inhibition of rabbit muscle PFK at 500 uM | Oryctolagus cuniculus | 1 | ALA1158635 | single protein format | Scientific Literature | |
7. | ALA1118358 | Binding | Inhibition of Trypanosoma brucei PFK expressed in Escherichia coli | Trypanosoma brucei | 3 | ALA1158635 | assay format | Scientific Literature | |
8. | ALA1118360 | Binding | Inhibition of rabbit muscle aldolase | Oryctolagus cuniculus | 3 | ALA1158635 | single protein format | Scientific Literature | |
9. | ALA1118363 | Binding | Inhibition of Trypanosoma brucei aldolase expressed in Escherichia coli | Trypanosoma brucei | 2 | ALA1158635 | assay format | Scientific Literature | |
10. | ALA1118365 | Binding | Selectivity ratio of IC50 for rabbit muscle aldolase to IC50 for Trypanosoma brucei aldolase | 1 | ALA1158635 | tissue-based format | Scientific Literature | ||
11. | ALA1118880 | Binding | Mixed-type reversible inhibition of Trypanosoma brucei GAPDH expressed in Escherichia coli using NAD+ by spectrophotometry analysis | Trypanosoma brucei | 1 | ALA1158635 | assay format | Scientific Literature | |
12. | ALA1118881 | Binding | Mixed-type reversible inhibition of Trypanosoma brucei GAPDH expressed in Escherichia coli at enzyme substrate complex by spectrophotometry analysis | Trypanosoma brucei | 1 | ALA1158635 | assay format | Scientific Literature |