# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1805603 | A | Displacement of radiolabeled warfarin from human serum albumin site 1 in phosphate buffer at pH 7.4 upto 12 uM by fluorescence spectroscopy | Homo sapiens | 4 | single protein format | Scientific Literature | ||
2. | ALA1805604 | A | Displacement of radiolabeled dansylsarcosine from human serum albumin site 2 in phosphate buffer at pH 7.4 upto 12 uM by fluorescence spectroscopy | Homo sapiens | 4 | single protein format | Scientific Literature | ||
3. | ALA1805612 | P | Aqueous solubility of the compound in phosphate buffer solution of pH 7.4 after 24 hrs by LC-UV analysis | 5 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA1805613 | A | Binding affinity to fatty acid-free human serum albumin by equilibrium dialysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
5. | ALA1805614 | A | Binding affinity to fatty acid-containing human serum albumin by equilibrium dialysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
6. | ALA1805615 | P | Octanol-buffer partition coefficient, log D of the compound at pH 7.4 by shake-flask method | 3 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA1805616 | P | Dissociation constant, pKa of the compound by spectrophotometric titration | 3 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA1805617 | P | Lipophilicity, log P of the compound in octanol | 3 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA1120661 | B | Inhibition of human recombinant liver glycogen phosphorylase by multienzyme-coupled reaction | Homo sapiens | 17 | assay format | Scientific Literature | ||
10. | ALA1120662 | A | Oral bioavailability in rat at 5 mg/kg oral & 2 mg/kg iv dose | Rattus norvegicus | 15 | organism-based format | Scientific Literature | ||
11. | ALA3301363 | P | ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake flask method described in J. Biomol. Screen. 2011, 16, 348-355. Experimental range -1.5 to 4.5 | 4,197 | small-molecule physicochemical format | AstraZeneca Deposited Data |