# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA618942 | ADME | Compound was measured for binding rate for human serum at a carbapenem concentration of 10 ug/mL | Homo sapiens | 6 | ALA1149970 | assay format | Scientific Literature | |
2. | ALA662336 | Functional | Relative rate of hydrolysis of porcine renal dehydropeptidase-I (DHP-I) to imipenem | Sus scrofa | 25 | ALA1149970 | assay format | Scientific Literature | |
3. | ALA662341 | Functional | Compound was measured for DHP-I susceptibility | 6 | ALA1149970 | assay format | Scientific Literature | ||
4. | ALA674685 | Functional | In vitro antibacterial activity against Enterococcus faecalis MB4996 organism | Enterococcus faecalis | 24 | ALA1149970 | organism-based format | Scientific Literature | |
5. | ALA677293 | Functional | In vitro antibacterial activity against Escherichia coli NIHJ JC2 organism | Escherichia coli | 24 | ALA1149970 | organism-based format | Scientific Literature | |
6. | ALA808915 | Functional | In vitro antibacterial activity against Staphylococcus epidermidis MB5181a organism | Staphylococcus epidermidis | 26 | ALA1149970 | organism-based format | Scientific Literature | |
7. | ALA811156 | Functional | Compound was tested in vitro for its anti-methicillin-resistant staphylococcus aureus(MRSA); 3.13-6.25 | Staphylococcus aureus | 4 | ALA1149970 | organism-based format | Scientific Literature | |
8. | ALA810370 | Functional | In vitro antibacterial activity against staphylococcus aureus 209P NIHJ JC1 organism | Staphylococcus aureus | 26 | ALA1149970 | organism-based format | Scientific Literature | |
9. | ALA810371 | Functional | In vitro antibacterial activity against staphylococcus aureus BB6294 organism (Methicillin-resistant strain) | Staphylococcus aureus | 26 | ALA1149970 | organism-based format | Scientific Literature | |
10. | ALA810372 | Functional | In vitro antibacterial activity against staphylococcus aureus CSa1009 (Methicillin-resistant strain and b beta-Lactamase producing strain) | Staphylococcus aureus | 26 | ALA1149970 | organism-based format | Scientific Literature | |
11. | ALA810038 | Functional | Compound was tested in vivo for its anti-methicillin-resistant staphylococcus aureus(MRSA) | Staphylococcus aureus | 8 | ALA1149970 | organism-based format | Scientific Literature | |
12. | ALA786592 | Functional | Epileptogenicity of compound was measured at 100 ug/rat head by the rat intraventricular assay; 0/5 | Rattus norvegicus | 4 | ALA1149970 | organism-based format | Scientific Literature | |
13. | ALA757160 | Functional | PBP-2'' affinity was determined by the competition assay with [14C]benzylpenicillin using membrane isolated from MRSA BB6294 strain | Staphylococcus aureus | 3 | ALA1149970 | assay format | Scientific Literature | |
14. | ALA743872 | Functional | Compound was measured for binding rate for mouse serum at a carbapenem concentration of 10 ug/mL | Mus musculus | 6 | ALA1149970 | organism-based format | Scientific Literature | |
15. | ALA770992 | Functional | In vitro antibacterial activity against Pseudomonas aeruginosa MB5002 organism | Pseudomonas aeruginosa | 24 | ALA1149970 | organism-based format | Scientific Literature |