# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA636394 | ADME | Delta logD (logD6.5 - logD7.4) | 152 | ALA1133765 | assay format | Scientific Literature | ||
2. | ALA646647 | Physicochemical | Partition coefficient (logD6.5) | 153 | ALA1133765 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA645153 | Physicochemical | Ionization constant (pKa) | 204 | ALA1133765 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA633099 | ADME | Oral bioavailability in human | Homo sapiens | 35 | ALA1133765 | organism-based format | Scientific Literature | |
5. | ALA651256 | Binding | Positive inotropic effects by direct or indirect beta-1 adrenergic receptor activation. | 17 | ALA1123575 | single protein format | Scientific Literature | ||
6. | ALA651193 | Binding | Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA) | 34 | ALA1123047 | single protein format | Scientific Literature | ||
7. | ALA653458 | Binding | Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA) | 34 | ALA1123047 | single protein format | Scientific Literature | ||
8. | ALA651146 | Binding | Dose necessary to produce 50% of the isoprenaline effect to inhibit GDP binding to beta-3 adrenergic receptor in brown adipose tissue (BAT mitochondria) of rats after subcutaneous administration. | 28 | ALA1126035 | mitochondrion format | Scientific Literature | ||
9. | ALA660997 | Functional | Intrinsic activity as percentage of heart rate (HR max) in cat was determined | Felis catus | 3 | ALA1121448 | organism-based format | Scientific Literature | |
10. | ALA658277 | Functional | Tested for agonistic effect on heart rate against beta-1 adrenergic receptor in cat | Felis catus | 3 | ALA1121448 | tissue-based format | Scientific Literature | |
11. | ALA666810 | Functional | Intrinsic sympathomimetic activity (ISA, calculated as the percent of maximum change in heart rate (HR) | Canis lupus familiaris | 45 | ALA1121799 | organism-based format | Scientific Literature | |
12. | ALA666811 | Functional | Intrinsic sympathomimetic activity (ISA), calculated as the percent of maximum change in hind limb perfusion pressure (HLPP) | Canis lupus familiaris | 45 | ALA1121799 | organism-based format | Scientific Literature | |
13. | ALA670853 | Functional | Effective dose required for the maximum heart rate in anesthetized dogs. | Canis lupus familiaris | 45 | ALA1121799 | organism-based format | Scientific Literature | |
14. | ALA670854 | Functional | Effective dose required for the maximum hind limb perfusion pressure(HLPP) in anesthetized dogs. | Canis lupus familiaris | 45 | ALA1121799 | organism-based format | Scientific Literature | |
15. | ALA678104 | Binding | Free energy of binding to turkey erythrocyte beta receptor | Meleagris gallopavo | 58 | ALA1123401 | assay format | Scientific Literature | |
16. | ALA819725 | Binding | Change in Gibb's free energy at Low affinity beta-2-adrenoceptor in the membranes of bovine skeletal muscle preparation | 26 | ALA1124120 | cell membrane format | Scientific Literature | ||
17. | ALA819728 | Binding | Change in Gibb's free energy at Low affinity beta-2-adrenoceptor in the Chang living cells | 36 | ALA1124120 | cell-based format | Scientific Literature | ||
18. | ALA845019 | Functional | Selectivity is expressed as the ratio of ED50 on hind limb perfusion pressure to the ED50 on heart rate | Canis lupus familiaris | 45 | ALA1121799 | organism-based format | Scientific Literature | |
19. | ALA840719 | Functional | Ratio of the dose (D500,subcutaneous administration) elevating the rat heart rate to 500 bpm to the GDP ED50 | 1 | ALA1126035 | organism-based format | Scientific Literature | ||
20. | ALA1697855 | ADME | Literature-mined public compounds from Kruhlak et al phospholipidosis modelling dataset | 484 | ALA1697821 | assay format | Scientific Literature |