# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA958132 | F | Immunosuppressive activity against human PBMC assessed as inhibition of allogenic mixed lymphocyte reaction | Homo sapiens | 44 | cell-based format | Scientific Literature | ||
2. | ALA958134 | F | Immunosuppressive activity against human PBMC assessed as inhibition of allogenic mixed lymphocyte reaction at 0.5 uM | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
3. | ALA958929 | F | Immunosuppressive activity against human PBMC assessed as inhibition of allogenic mixed lymphocyte reaction at 0.1 uM | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
4. | ALA1021370 | F | Antibacterial activity against Staphylococcus aureus ATCC 25923 at 30 nmol after 16 to 20 hrs | Staphylococcus aureus | 25 | organism-based format | Scientific Literature | ||
5. | ALA1021371 | F | Antibacterial activity against Enterococcus faecalis ATCC 29212 at 30 nmol after 16 to 20 hrs | Enterococcus faecalis | 25 | organism-based format | Scientific Literature | ||
6. | ALA1021372 | F | Antibacterial activity against wild type Escherichia coli at 30 nmol after 16 to 20 hrs | Escherichia coli | 25 | organism-based format | Scientific Literature | ||
7. | ALA1021373 | F | Antibacterial activity against Escherichia coli delta ABN mutant lacking peptidase A, B, N at 30 nmol after 16 to 20 hrs | Escherichia coli | 14 | organism-based format | Scientific Literature | ||
8. | ALA4197602 | B | Inhibition of Leucyl-tRNA synthetase in Escherichia coli K-12 BW28357 S30 extract assessed as reduction in tRNA aminoacylation at 2.5 uM preincubated for 5 mins followed by Escherichia coli tRNA and 14C-labeled leucine addition measured after 5 mins by liquid scintillation counting method relative to control | Escherichia coli K-12 | 2 | single protein format | Scientific Literature | ||
9. | ALA4197608 | B | Inhibition of Escherichia coli BL21(DE3) Leucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichia coli tRNA and 14C-labeled leucine followed by ATP addition by liquid scintillation counting method | Escherichia coli BL21(DE3) | 2 | single protein format | Scientific Literature | ||
10. | ALA4197613 | F | Antibacterial activity against Staphylococcus aureus ATCC 65381 up to 100 uM after 18 to 24 hrs by two fold serial dilution method | Staphylococcus aureus | 12 | organism-based format | Scientific Literature | ||
11. | ALA4197614 | F | Antibacterial activity against Staphylococcus epidermidis RP62A up to 100 uM after 18 to 24 hrs by two fold serial dilution method | Staphylococcus epidermidis | 12 | organism-based format | Scientific Literature | ||
12. | ALA4197615 | F | Antibacterial activity against Kocuria rhizophila ATCC 9341 up to 100 uM after 18 to 24 hrs by two fold serial dilution method | Kocuria rhizophila | 12 | organism-based format | Scientific Literature | ||
13. | ALA4197616 | F | Antibacterial activity against Escherichia coli NCIB 8743 up to 100 uM after 18 to 24 hrs by two fold serial dilution method | Escherichia coli | 12 | organism-based format | Scientific Literature | ||
14. | ALA4197617 | F | Antibacterial activity against Pseudomonas aeruginosa PAO1 up to 100 uM after 18 to 24 hrs by two fold serial dilution method | Pseudomonas aeruginosa | 12 | organism-based format | Scientific Literature | ||
15. | ALA4370819 | B | Inhibition of Leucyl-tRNA synthetase-mediated mTORC1 signaling activation in human HEK293 cells assessed as reduction in leucine-induced S6K phosphorylation at 200 uM preincubated for 50 mins followed by leucine-stimulation and measured after 10 mins by Western blot analysis | Homo sapiens | 48 | cell-based format | Scientific Literature | ||
16. | ALA4394777 | B | Inhibition of leuRS in Escherichia coli NCIB 8743 S30 extract assessed as aminoacylation at 250 nM incubated for 5 mins in presence of 14C-labeled leucine by liquid scintillation counting method relative to control | Escherichia coli | 4 | single protein format | Scientific Literature | ||
17. | ALA4394786 | B | Inhibition of ileRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing RimI incubated for 5 to 60 mins in presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli BL21(DE3) | 9 | single protein format | Scientific Literature | ||
18. | ALA4394787 | B | Inhibition of leuRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing RimI incubated for 5 to 60 mins in presence of 14C-labeled leucine by liquid scintillation counting method | Escherichia coli BL21(DE3) | 9 | single protein format | Scientific Literature | ||
19. | ALA4394788 | B | Inhibition of tyrRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing RimI incubated for 5 to 60 mins in presence of 14C-labeled tyrosine by liquid scintillation counting method | Escherichia coli BL21(DE3) | 9 | single protein format | Scientific Literature | ||
20. | ALA4394789 | B | Inhibition of ileRS in Escherichia coli BL21 (DE3) pLysS S30 extract over expressing SUMO incubated for 5 to 60 mins in presence of 14C-labeled isoleucine and acetyl-CoA by liquid scintillation counting method | Escherichia coli BL21(DE3) | 9 | single protein format | Scientific Literature |