| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1175304 | Binding | Binding affinity to Influenza A Weybridge(H7N7) virus Matrix protein 2 by spectrophotometry | Influenza A virus (A/chicken/FPV/Weybridge(H7N7)) | 18 | ALA1177798 | single protein format | Scientific Literature | |
| 2. | ALA3292604 | Binding | Blockade of Influenza A virus (A/England/195/2009(H1N1)) full length M2 proton channel expressed in HEK cells after 3 mins by voltage clamp technique | Influenza A virus (A/California/07/2009(H1N1)) | 3 | ALA3286127 | cell-based format | Scientific Literature | |
| 3. | ALA3292605 | Binding | Blockade of Influenza A virus (A/England/195/2009(H1N1)) full length M2 S31N mutant expressed in HEK cells at 100 uM after 3 mins by voltage clamp technique | Influenza A virus (A/England/195/2009(H1N1)) | 3 | ALA3286127 | cell-based format | Scientific Literature | |
| 4. | ALA3292606 | Binding | Blockade of Influenza A virus (A/England/195/2009(H1N1)) full length M2 S31N mutant expressed in HEK cells at 100 uM after 30 mins by voltage clamp technique | Influenza A virus (A/California/08/2009(H1N1)) | 2 | ALA3286127 | cell-based format | Scientific Literature | |
| 5. | ALA3292607 | Binding | Blockade of Influenza A virus (A/England/195/2009(H1N1)) full length M2 proton channel expressed in HEK cells at 10 uM after 3 mins by voltage clamp technique | Influenza A virus (A/California/07/2009(H1N1)) | 3 | ALA3286127 | cell-based format | Scientific Literature | |
| 6. | ALA3292608 | Functional | Antiviral activity against Influenza A virus (A/California/07/2009(H1N1)) infected in MDCK cells expressing M2 S31N mutant after overnight incubation by fluorescence-based miniplaque assay | Influenza A virus (A/California/07/2009(H1N1)) | 11 | ALA3286127 | cell-based format | Scientific Literature | |
| 7. | ALA3292609 | Functional | Antiviral activity against Influenza A virus (A/Puerto Rico/8/34(H1N1)) infected in MDCK cells expressing M2 V27T/S31N mutant after overnight incubation by fluorescence-based miniplaque assay | Influenza A virus | 11 | ALA3286127 | organism-based format | Scientific Literature | |
| 8. | ALA3292857 | Functional | Antiviral activity against Influenza A virus A/WS/33(H1N1) infected in MDCK cells expressing M2 S31N mutant after overnight incubation by fluorescence-based miniplaque assay | Influenza A virus | 11 | ALA3286127 | organism-based format | Scientific Literature | |
| 9. | ALA3292858 | Functional | Antiviral activity against Influenza A virus A2/Taiwan/1/64(H2N2) infected in MDCK cells expressing wild type M2 after overnight incubation by fluorescence-based miniplaque assay | Influenza A virus | 11 | ALA3286127 | organism-based format | Scientific Literature | |
| 10. | ALA3292859 | Functional | Antiviral activity against Influenza A virus A/Victoria/3/75(H3N2) infected in MDCK cells expressing wild type M2 after overnight incubation by fluorescence-based miniplaque assay | Influenza A virus | 11 | ALA3286127 | organism-based format | Scientific Literature | |
| 11. | ALA3292860 | ADME | Cytotoxicity against MDCK cells at 50 uM after 18 hrs | Canis lupus familiaris | 10 | ALA3286127 | cell-based format | Scientific Literature | |
| 12. | ALA3292876 | Functional | Antiviral activity against Influenza B virus B/Russia/69 infected in MDCK cells at 50 uM | Influenza B virus | 4 | ALA3286127 | organism-based format | Scientific Literature | |
| 13. | ALA4005522 | Binding | Binding affinity to synthetic wild-type C-terminally amidated Influenza A virus (A/Udorn/307/72) M2 transmembrane domain (22 to 46 residues) in DPC micelles at pH 8 by ITC method | Influenza A virus (A/Udorn/307/1972(H3N2)) | 10 | ALA4004820 | assay format | Scientific Literature | |
| 14. | ALA4005523 | Binding | Binding affinity to synthetic Influenza A virus (A/Udorn/307/72) M2 transmembrane domain S31N mutant (22 to 46 residues) in DPC micelles measured at pH 8 by ITC method | Influenza A virus (A/Udorn/307/1972(H3N2)) | 10 | ALA4004820 | assay format | Scientific Literature | |
| 15. | ALA4005531 | Binding | Inhibition of Influenza A virus (A/California/07/2009(H1N1)) M2 proton channel S31N mutant expressed in HEK cells assessed as inhibition of low-pH-dependent inward proton currents at 10 uM and pH 5.5 measured after 3 mins in presence of CaCl2 by electrophysiology method | Influenza A virus (A/California/07/2009(H1N1)) | 5 | ALA4004820 | cell-based format | Scientific Literature | |
| 16. | ALA4005532 | Binding | Inhibition of Influenza A virus (A/California/07/2009(H1N1)) M2 proton channel S31N mutant expressed in HEK cells assessed as inhibition of low-pH-dependent inward proton currents at pH 5.5 in presence of CaCl2 by electrophysiology method | Influenza A virus (A/California/07/2009(H1N1)) | 5 | ALA4004820 | cell-based format | Scientific Literature | |
| 17. | ALA4005533 | Functional | Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing M2 proton channel S31N mutant infected in MDCK cells assessed as reduction in cytopathic effect after 48 hrs by crystal violet staining-based microscopic analysis | Influenza A virus (A/WSN/1933(H1N1)) | 11 | ALA4004820 | cell-based format | Scientific Literature | |
| 18. | ALA4005534 | Functional | Antiviral activity against Influenza A virus (A/WSN/1933(H1N1)) expressing wild-type M2 proton channel infected in MDCK cells assessed as reduction in cytopathic effect after 48 hrs by crystal violet staining-based microscopic analysis | Influenza A virus (A/WSN/1933(H1N1)) | 11 | ALA4004820 | cell-based format | Scientific Literature | |
| 19. | ALA4005535 | ADME | Cytotoxicity against MDCK cells measured after 72 hrs et staining-based microscopic analysis | Canis lupus familiaris | 11 | ALA4004820 | cell-based format | Scientific Literature | |
| 20. | ALA4005539 | Binding | Binding affinity to synthetic wild-type C-terminally amidated Influenza A virus (A/Udorn/307/72) M2 transmembrane domain (22 to 46 residues) in DPC micelles assessed as deltaG values at pH 8 by ITC method | Influenza A virus (A/Udorn/307/1972(H3N2)) | 10 | ALA4004820 | assay format | Scientific Literature |
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