# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1175693 | B | Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation counting | Plasmodium falciparum | 27 | assay format | Scientific Literature | ||
2. | ALA1175694 | B | Inhibition of human CDK7/Cyclin H/MAT1 | Homo sapiens | 6 | protein complex format | Scientific Literature | ||
3. | ALA1175695 | B | Inhibition of human CDK6/Cyclin D1 | Homo sapiens | 6 | protein complex format | Scientific Literature | ||
4. | ALA1175696 | B | Inhibition of human CDK1/cyclin B | Homo sapiens | 6 | protein complex format | Scientific Literature | ||
5. | ALA1175697 | B | Inhibition of human CDK2/Cyclin A | Homo sapiens | 6 | protein complex format | Scientific Literature | ||
6. | ALA1175698 | F | Antimalarial activity against chloroquine-resistant Plasmodium falciparum W2 assessed as inhibition of [3H]hypoxanthine incorporation after 24 hrs by microtiter plate scintillation counting | Plasmodium falciparum | 9 | organism-based format | Scientific Literature | ||
7. | ALA1175699 | A | Cytotoxicity against mouse RAW264.7 cells after 24 hrs by MTT assay | Mus musculus | 9 | cell-based format | Scientific Literature | ||
8. | ALA1175700 | F | Cytotoxicity against human DU145 cells after 24 hrs by MTT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
9. | ALA1175701 | F | Cytotoxicity against human LoVo cells after 24 hrs by MTT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
10. | ALA1175702 | F | Cytotoxicity against human Hs578 cells after 24 hrs by MTT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
11. | ALA1175703 | F | Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
12. | ALA1175704 | A | Therapeutic index, IC50 for Plasmodium falciparum W2 to IC50 for mice (Mus musculus) RAW264.7 cells | 2 | cell-based format | Scientific Literature | |||
13. | ALA4704712 | B | Agonist activity at human FFA4 receptor expressed in CHO-K1 cells assessed as increase in amplitude of dynamic mass redistribution response by DMR assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
14. | ALA4704713 | B | Agonist activity at human FFA4 receptor expressed in CHO-K1 cells assessed as efficacy of increase in amplitude of dynamic mass redistribution response by DMR assay relative to control | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
15. | ALA4704714 | B | Agonist activity at human FFA1 receptor expressed in CHO-K1 cells assessed as increase in dynamic mass redistribution response by DMR assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
16. | ALA4704715 | B | Selectivity index, ratio of EC50 for agonist activity at human FFA1 receptor expressed in CHO-K1 cells to EC50 for agonist activity at human FFA4 receptor expressed in CHO-K1 cells by DMR assay | Homo sapiens | 21 | cell-based format | Scientific Literature |