| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1176449 | B | Inhibition of human Gli1 expressed in mouse C3H10T1/2 cells assessed as inhibition of transcriptional activity after 24 hrs by luciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA1176450 | A | Half life in CD-1 mouse liver microsomes | Mus musculus | 4 | microsome format | Scientific Literature | ||
| 3. | ALA1176640 | B | Inhibition of human Gli2 expressed in mouse C3H10T1/2 cells assessed as inhibition of transcriptional activity after 24 hrs by luciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA1176641 | B | Selectivity ratio of IC50 for human Gli1-mediated transcriptional activity to IC50 for human Gli2-mediated transcriptional activity | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 5. | ALA1176642 | B | Inhibition of HDAC up to 40 uM | 4 | assay format | Scientific Literature | |||
| 6. | ALA1176645 | B | Inhibition of human Gli1-mediated transcriptional activity in human Rh30 cells at 10 to 20 uM after 24 hrs by luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA1176646 | F | Inhibition of Ptch1 expression in human Rh30 cells at 10 to 40 uM after 24 hrs by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA1176647 | F | Inhibition of Bcl2 expression in human Rh30 cells at 10 to 40 uM after 24 hrs by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA1176648 | F | Inhibition of cyclinD1 expression in human Rh30 cells at 10 to 40 uM after 24 hrs by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA1176649 | F | Cytotoxicity against human Rh30 cells at 5 to 20 uM after 72 hrs by Alamar blue assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 11. | ALA1176650 | A | Cytotoxicity against human BJ cells at 5 to 20 uM after 72 hrs by Alamar blue assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 12. | ALA1176651 | A | Permeability in buffer of pH 7.4 by PAMPA | 6 | assay format | Scientific Literature | |||
| 13. | ALA1176655 | B | Inhibition of transcriptional activity of AP1 transfected in mouse C3H10T1/2 cells at 20 uM after 24 hrs by luciferase reporter gene assay | 4 | cell-based format | Scientific Literature | |||
| 14. | ALA1176656 | F | Inhibition of Hh signal-induced alkaline phosphatase activity in mouse C3H10T1/2 cells at 10 uM after 4 days | Mus musculus | 3 | cell-based format | Scientific Literature |
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