# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA972809 | B | Inhibition of pancreatic lipase assessed as umoles of oleic acic released per millimiter of triolein per hour at 1 mg/mL | 15 | single protein format | Scientific Literature | |||
2. | ALA1177375 | B | Inhibition of COX2 by microplate reader | 24 | single protein format | Scientific Literature | |||
3. | ALA1177376 | B | Inhibition of COX1 by microplate reader | 24 | single protein format | Scientific Literature | |||
4. | ALA3862786 | F | Inhibition of amyloid beta (25 to 35)-induced neuronal degeneration in ddY mouse embryo cortical neurons assessed as restoration of axonal outgrowth by measuring length of phosphorylated neurofilament-H-positive neurites at 10 uM treated 3 days post amyloid beta (25 to 35) stimulation measured after 4 days by fluorescent microscopic analysis | Mus musculus | 16 | assay format | Scientific Literature | ||
5. | ALA4136503 | F | Cytoprotection against H2O2-induced cell injury in rat PC12 cells assessed as increase in cell viability at 1 to 10 uM preincubated for 12 hrs followed by H2O2 addition measured after 12 hrs by MTT assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
6. | ALA4136504 | A | Cytotoxicity against rat PC12 cells assessed as decrease in cell viability at 50 uM after 12 hrs by MTT assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
7. | ALA4136508 | F | Cytoprotection against amyloid beta (1 to 42)-induced cell injury in rat PC12 cells assessed as cell viability at 10 uM preincubated for 12 hrs followed by amyloid beta (1 to 42) addition measured after 12 hrs by MTT assay (Rvb = 55.3 +/- 1.5%) | Rattus norvegicus | 11 | cell-based format | Scientific Literature | ||
8. | ALA4136509 | F | Cytoprotection against amyloid beta (1 to 42)-induced cell injury in rat PC12 cells assessed as cell viability at 50 uM preincubated for 12 hrs followed by amyloid beta (1 to 42) addition measured after 12 hrs by MTT assay (Rvb = 55.3 +/- 1.5%) | Rattus norvegicus | 11 | cell-based format | Scientific Literature | ||
9. | ALA4136510 | F | Cytoprotection against amyloid beta (1 to 42)-induced cell injury in rat PC12 cells assessed as cell viability at 100 uM preincubated for 12 hrs followed by amyloid beta (1 to 42) addition measured after 12 hrs by MTT assay (Rvb = 55.3 +/- 1.5%) | Rattus norvegicus | 11 | cell-based format | Scientific Literature | ||
10. | ALA4136511 | F | Cytoprotection against amyloid beta (1 to 42)-induced toxicity in rat PC12 cells assessed as LDH release at 10 uM preincubated with cells followed by amyloid beta (1 to 42) addition measured after 24 hrs by LDH assay (Rvb = 153%) | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
11. | ALA4136512 | F | Cytoprotection against amyloid beta (1 to 42)-induced toxicity in rat PC12 cells assessed as LDH release at 50 uM preincubated with cells followed by amyloid beta (1 to 42) addition measured after 24 hrs by LDH assay (Rvb = 153%) | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
12. | ALA4136513 | F | Cytoprotection against amyloid beta (1 to 42)-induced toxicity in rat PC12 cells assessed as LDH release at 100 uM preincubated with cells followed by amyloid beta (1 to 42) addition measured after 24 hrs by LDH assay (Rvb = 153%) | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
13. | ALA4136514 | F | Cytoprotection against amyloid beta (1 to 42)-induced oxidative damage in rat PC12 cells assessed as intracellular ROS level at 10 uM preincubated with cells followed by amyloid beta (1 to 42) addition measured after 24 hrs by DCFH-DA staining based flow cytometry (Rvb = 51.4%) | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
14. | ALA4136515 | F | Cytoprotection against amyloid beta (1 to 42)-induced oxidative damage in rat PC12 cells assessed as intracellular ROS level at 50 uM preincubated with cells followed by amyloid beta (1 to 42) addition measured after 24 hrs by DCFH-DA staining based flow cytometry (Rvb = 51.4%) | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
15. | ALA4136516 | F | Cytoprotection against amyloid beta (1 to 42)-induced oxidative damage in rat PC12 cells assessed as intracellular ROS level at 100 uM preincubated with cells followed by amyloid beta (1 to 42) addition measured after 24 hrs by DCFH-DA staining based flow cytometry (Rvb = 51.4%) | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
16. | ALA4136517 | F | Cytoprotection against amyloid beta (1 to 42)-induced oxidative damage in rat PC12 cells assessed as reduction in intracellular ROS level preincubated with cells followed by amyloid beta (1 to 42) addition measured after 24 hrs by DCFH-DA staining based flow cytometry | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
17. | ALA4136518 | F | Cytoprotection against amyloid beta (1 to 42)-induced damage in rat PC12 cells assessed as reduction in intracellular MDA level preincubated with cells followed by amyloid beta (1 to 42) addition measured after 24 hrs by TBA assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
18. | ALA4136519 | F | Cytoprotection against amyloid beta (1 to 42)-induced damage in rat PC12 cells assessed as intracellular MDA level at 10 uM preincubated with cells followed by amyloid beta (1 to 42) addition measured after 24 hrs by TBA assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
19. | ALA4136520 | F | Cytoprotection against amyloid beta (1 to 42)-induced damage in rat PC12 cells assessed as intracellular MDA level at 50 uM preincubated with cells followed by amyloid beta (1 to 42) addition measured after 24 hrs by TBA assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
20. | ALA4136521 | F | Cytoprotection against amyloid beta (1 to 42)-induced damage in rat PC12 cells assessed as intracellular MDA level at 100 uM preincubated with cells followed by amyloid beta (1 to 42) addition measured after 24 hrs by TBA assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature |