# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2049708 | B | Inhibition of recombinant fluorescein-tagged E1 assessed as inhibition of ubiquitin-E1 adduct formation incubated for 15 mins prior to ATP addition measured after 5 mins by SDS PAGE analysis | 1 | single protein format | Scientific Literature | |||
2. | ALA1919515 | F | Growth inhibition of human HCT116 cells after 96 hrs by MTS assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
3. | ALA1919517 | B | Inhibition of recombinant HDAC1 at 1 uM after 1 hr by fluorimetric assay | 4 | single protein format | Scientific Literature | |||
4. | ALA1919518 | B | Inhibition of HDAC1 from human HeLa nuclear extract after 1 hr by fluorimetric assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
5. | ALA1919519 | B | Inhibition of HDAC6 from human HeLa nuclear extract after 1 hr by fluorimetric assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
6. | ALA1919520 | B | Inhibition of recombinant HDAC6 at 1 uM after 1 hr by fluorimetric assay | 4 | single protein format | Scientific Literature | |||
7. | ALA1917997 | B | Inhibition of HDAC1 in human HCT116 cells assessed as increase in histone H3 acetylation at 10 nM after 24 hrs by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
8. | ALA1917998 | B | Inhibition of HDAC1 in human HCT116 cells assessed as increase in histone H3 acetylation at 100 nM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA1918000 | B | Inhibition of HDAC6 in human HCT116 cells assessed as increase in alpha tubulin acetylation at 0.01 to 1 uM after 24 hrs by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
10. | ALA1681080 | A | Cytotoxicity against mouse C2C12 cells up to 100 uM after 3 days | Mus musculus | 1 | cell-based format | Scientific Literature | ||
11. | ALA1681081 | B | Inhibition of HDAC in mouse C2C12 cells at 5 to 100 nM after 24 hrs by fluorescence assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
12. | ALA1681082 | B | Inhibition of HDAC in mouse C2C12 cells assessed as increase of acetylated histone level after 24 hrs by Western blotting | Mus musculus | 1 | cell-based format | Scientific Literature | ||
13. | ALA1681083 | F | Induction of osteoblast differentiation in mouse C2C12 cells assessed as increase of alkaline phosphatase expression after 6 days | Mus musculus | 1 | cell-based format | Scientific Literature | ||
14. | ALA1681084 | F | Induction of osteoblast differentiation in mouse C2C12 cells assessed as increase of osteopontin expression up to 100 nM after 6 days | Mus musculus | 1 | cell-based format | Scientific Literature | ||
15. | ALA1681085 | B | Activation of Runx2 activity in mouse C2C12 cells at 50 nM after 24 hrs by luciferase reporter gene assay relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
16. | ALA1679101 | F | Osteogenic activity in mouse C2C12 cells assessed as increase of Runx2 mRNA expression at 50 nM after 6 days by RT-PCR analysis relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
17. | ALA1679102 | F | Osteogenic activity in mouse C2C12 cells assessed as increase of BMP2 mRNA expression at up to 50 nM after 6 days by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
18. | ALA1679103 | F | Osteogenic activity in mouse C2C12 cells assessed as increase of BMP4 mRNA expression at up to 50 nM after 6 days by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
19. | ALA1679104 | F | Osteogenic activity in mouse C2C12 cells assessed as increase of BMP6 mRNA expression at up to 50 nM after 6 days by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
20. | ALA1679105 | F | Osteogenic activity in mouse C2C12 cells assessed as increase of BMP7 mRNA expression at up to 50 nM after 6 days by RT-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature |