# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1930654 | F | Activation of rat TAAR1 expressed in Syrian hamster AV12-664 cells assessed as accumulation of cAMP after 30 mins using cAMP XS EA/CL as substrate by luminescence method | Rattus norvegicus | 4 | ALA1926662 | cell-based format | Scientific Literature | |
2. | ALA1930658 | F | Activation of human TAAR1 expressed in Syrian hamster AV12-664 cells co-expressing GalphaS protein assessed as accumulation of cAMP after 30 mins using cAMP XS EA/CL as substrate by luminescence method in presence of RX821002 and alprenolol | Homo sapiens | 4 | ALA1926662 | cell-based format | Scientific Literature | |
3. | ALA3583705 | F | Agonist activity at mouse TAAR1 expressed in HEK293 cells coexpressing cAMP BRET biosensor assessed as induction of CAMP production after 20 mins by bioluminescence resonance energy transfer assay | Mus musculus | 6 | ALA3580610 | cell-based format | Scientific Literature | |
4. | ALA3583710 | F | Reduction in cardiac out put in male Wistar rat heart assessed as aortic and coronary flow after 30 mins by Cardiac perfusion technique | Rattus norvegicus | 5 | ALA3580610 | tissue-based format | Scientific Literature | |
5. | ALA3788457 | F | Agonist activity at mouse TAAR1 expressed in HEK293 cells assessed as increase in cAMP release after 30 mins by BRET assay | Mus musculus | 1 | ALA3784953 | cell-based format | Scientific Literature | |
6. | ALA3788458 | F | Agonist activity at human TAAR1 expressed in HEK293 cells assessed as increase in cAMP release after 30 mins by BRET assay | Homo sapiens | 1 | ALA3784953 | cell-based format | Scientific Literature | |
7. | ALA3788459 | F | Agonist activity at mouse TAAR5 expressed in HEK293 cells assessed as increase in cAMP release after 30 mins by BRET assay relative to control | Mus musculus | 2 | ALA3784953 | cell-based format | Scientific Literature | |
8. | ALA3788460 | B | Inverse agonist activity at human TAAR5 expressed in HEK293 cells by Alphascreen assay | Homo sapiens | 1 | ALA3784953 | cell-based format | Scientific Literature | |
9. | ALA3992915 | F | Inhibition of full length recombinant human N-terminal HA-tagged/C-terminal FLAG-tagged TAAR1 expressed in CHOK1 cells assessed as increase in cAMP accumulation by AlphaScreen assay | Homo sapiens | 1 | ALA3992498 | cell-based format | Scientific Literature | |
10. | ALA4719460 | F | Hyperglycemic activity in human HepG2 cells incubated for 4 hrs by colorimetric glucose assay | Homo sapiens | 1 | ALA4715788 | cell-based format | Scientific Literature | |
11. | ALA4719465 | B | Agonist activity at mouse TAAR1 | Mus musculus | 3 | ALA4715788 | single protein format | Scientific Literature | |
12. | ALA5036217 | F | Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as increase in intracellular cAMP incubated for 30 mins by HTRF analysis | Homo sapiens | 27 | ALA5034042 | cell-based format | Scientific Literature | |
13. | ALA5036218 | F | Agonist activity at recombinant human TAAR1 expressed in CHO-K1 cells assessed as maximal increase in intracellular cAMP incubated for 30 mins by HTRF analysis relative to control | Homo sapiens | 27 | ALA5034042 | cell-based format | Scientific Literature | |
14. | ALA5231636 | B | Non-competitive inhibition of bovine heart mitochondrial F0F1-ATP synthase incubated for 25 mins by ATPase assay | Bos taurus | 1 | ALA5230122 | mitochondrion format | Scientific Literature |