# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3436190 | Functional | Inhibition of Cav1.2 current measured using QPatch automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subunits | Cricetulus griseus | 1 | ALA3436045 | cell-based format | Scientific Literature | |
2. | ALA3537687 | ADME | Unbound fraction in plasma (unknown origin) under normal atmospheric condition at pH 7.22 after 6 hrs by equilibrium dialysis method | Not specified | 22 | ALA3526113 | cell-free format | Scientific Literature | |
3. | ALA3537688 | ADME | Unbound fraction in plasma (unknown origin) at pH 7.4 after 6 hrs by equilibrium dialysis method in presence of 5% CO2 | Not specified | 22 | ALA3526113 | cell-free format | Scientific Literature | |
4. | ALA3537689 | ADME | Unbound fraction in plasma (unknown origin) at pH 7.63 after 6 hrs by equilibrium dialysis method in presence of 5% CO2 | Not specified | 22 | ALA3526113 | cell-free format | Scientific Literature | |
5. | ALA3537690 | ADME | Unbound fraction in plasma (unknown origin) under normal atmospheric condition at pH 7.72 after 6 hrs by equilibrium dialysis method | Not specified | 22 | ALA3526113 | cell-free format | Scientific Literature | |
6. | ALA3537691 | ADME | Drug recovery in plasma (unknown origin) | Not specified | 22 | ALA3526113 | cell-free format | Scientific Literature | |
7. | ALA3537176 | ADME | Fraction unbound in Wistar Han rat brain homogenates at 1 uM after 6 hrs by equilibrium dialysis method | Rattus norvegicus | 46 | ALA3525956 | tissue-based format | Scientific Literature | |
8. | ALA3537177 | ADME | Fraction unbound in Sprague-Dawley rat brain homogenates at 1 uM after 6 hrs by equilibrium dialysis method | Rattus norvegicus | 46 | ALA3525956 | tissue-based format | Scientific Literature | |
9. | ALA3537178 | ADME | Fraction unbound in CD-1 mouse brain homogenates at 1 uM after 6 hrs by equilibrium dialysis method | Mus musculus | 46 | ALA3525956 | tissue-based format | Scientific Literature | |
10. | ALA3537179 | ADME | Fraction unbound in Hartley guinea pig brain homogenates at 1 uM after 6 hrs by equilibrium dialysis method | Cavia porcellus | 46 | ALA3525956 | tissue-based format | Scientific Literature | |
11. | ALA3537180 | ADME | Fraction unbound in Beagle dog brain homogenates at 1 uM after 6 hrs by equilibrium dialysis method | Canis lupus familiaris | 46 | ALA3525956 | tissue-based format | Scientific Literature | |
12. | ALA3537181 | ADME | Fraction unbound in cynomolgus monkey brain homogenates at 1 uM after 6 hrs by equilibrium dialysis method | Macaca fascicularis | 46 | ALA3525956 | tissue-based format | Scientific Literature | |
13. | ALA3537182 | ADME | Fraction unbound in human occipital cortex at 1 uM after 6 hrs by equilibrium dialysis method | Homo sapiens | 46 | ALA3525956 | assay format | Scientific Literature | |
14. | ALA3534719 | ADME | Fraction unbound in Wistar rat brain homogenate at 5 uM after 5 hrs by equilibrium dialysis method | Rattus norvegicus | 27 | ALA3526149 | tissue-based format | Scientific Literature | |
15. | ALA3534720 | ADME | Percentage unbound in solid supported porcine brain membrane vesicles at 5 uM by TRANSIL assay | Sus scrofa | 27 | ALA3526149 | tissue-based format | Scientific Literature | |
16. | ALA3534724 | ADME | Ratio of fraction unbound in Wistar rat brain homogenate at 5 uM after 5 hrs by equilibrium dialysis method to fraction unbound in solid supported porcine brain membrane vesicles at 5 uM by TRANSIL assay | 17 | ALA3526149 | tissue-based format | Scientific Literature | ||
17. | ALA3530456 | Physicochemical | Dissociation constant, pKa of the compound | 21 | ALA3526113 | small-molecule physicochemical format | Scientific Literature | ||
18. | ALA3528720 | ADME | Drug uptake in lysosomes of human Fa2N-4 cells assessed as inhibition of LysoTracker Red fluorescence after 30 mins | Homo sapiens | 27 | ALA3525994 | cell-based format | Scientific Literature | |
19. | ALA3529395 | ADME | Cytotoxicity against human Fa2N-4 cells by lactate dehydrogenase assay | Homo sapiens | 27 | ALA3525994 | cell-based format | Scientific Literature | |
20. | ALA3529441 | Physicochemical | Dissociation constant, pKa of the compound | 73 | ALA3526022 | small-molecule physicochemical format | Scientific Literature |
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- Homologous single protein target assigned 208
- Target assigned is non-molecular 146
- Direct single protein target assigned 115
- Default value - Target unknown or has yet to be assigned 113
- Multiple homologous protein targets may be assigned 6
- Multiple direct protein targets may be assigned 3
- Target assigned is molecular non-protein target 2
- Target assigned is subcellular fraction 1
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