| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA615820 | B | Binding affinity against 5-hydroxytryptamine 1A receptor (5-HT1A) by displacement of [3H]8-OH-DPAT from rat hippocampus membranes | 80 | cell membrane format | Scientific Literature | |||
| 2. | ALA617124 | B | Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]-ketanserin from rat prefrontal cerebral cortex mambranes | 71 | tissue-based format | Scientific Literature | |||
| 3. | ALA618310 | A | Unbound fraction (plasma) | Homo sapiens | 120 | cell-free format | Scientific Literature | ||
| 4. | ALA624569 | A | Observed volume of distribution | Homo sapiens | 120 | organism-based format | Scientific Literature | ||
| 5. | ALA633292 | P | Ionization constant (pKa) | 80 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA636394 | A | Delta logD (logD6.5 - logD7.4) | 152 | assay format | Scientific Literature | |||
| 7. | ALA646647 | P | Partition coefficient (logD6.5) | 153 | small-molecule physicochemical format | Scientific Literature | |||
| 8. | ALA645153 | P | Ionization constant (pKa) | 204 | small-molecule physicochemical format | Scientific Literature | |||
| 9. | ALA633100 | A | Oral bioavailability in human | Homo sapiens | 46 | organism-based format | Scientific Literature | ||
| 10. | ALA648038 | B | Evaluated for affinity at Alpha-1 adrenergic receptor of rat brain using [3H]prazosin as radioligand in radioligand binding assay | 5 | assay format | Scientific Literature | |||
| 11. | ALA875016 | B | Ability to displace [3H]rauwolscine from Alpha-2 adrenergic receptor in rat cortical membranes | 61 | cell membrane format | Scientific Literature | |||
| 12. | ALA649625 | B | Evaluated for affinity at Alpha-2 adrenergic receptor of rat brain using [3H]rauwolscine as radioligand in radioligand binding assay | 4 | assay format | Scientific Literature | |||
| 13. | ALA674997 | B | Equilibrium dissociation constant (KD) for Competitive binding between [3H]WIN-35428 and the compound at human transporter-hDAT | 18 | single protein format | Scientific Literature | |||
| 14. | ALA673202 | B | Binding affinity against dopamine transporter (DAT) by displacement of [3H]WIN-35428 in male wistar rats | 17 | single protein format | Scientific Literature | |||
| 15. | ALA673203 | B | Displacement of [3H]WIN-35428(0.5 nM) from Dopamine transporter | Rattus norvegicus | 11 | single protein format | Scientific Literature | ||
| 16. | ALA676686 | B | Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranes | 9 | cell membrane format | Scientific Literature | |||
| 17. | ALA739781 | F | Tested in vivo for head twitches antagonizing activity in mice | Mus musculus | 25 | organism-based format | Scientific Literature | ||
| 18. | ALA740206 | B | Tested in vitro for dopamine(DA) neuronal uptake inhibition | 27 | single protein format | Scientific Literature | |||
| 19. | ALA740207 | B | Tested in vitro for norepinephrine (NE) neuronal uptake inhibition | 27 | single protein format | Scientific Literature | |||
| 20. | ALA740208 | B | Tested in vitro for serotonin(5-HT) neuronal uptake inhibition | 28 | single protein format | Scientific Literature |
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