# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3832785 | F | AntiTrypanosoma cruzi activity IC50 (uM) | Trypanosoma cruzi | 65 | ALA3832761 | organism-based format | MMV Pathogen Box | |
2. | ALA3832786 | F | AntiTrypanosoma brucei activity T. b. brucei IC50 (uM) | Trypanosoma brucei | 64 | ALA3832761 | organism-based format | MMV Pathogen Box | |
3. | ALA3832787 | F | AntiTrypanosoma brucei activity T. b. rhodesiense IC50 (uM) | Trypanosoma brucei | 62 | ALA3832761 | organism-based format | MMV Pathogen Box | |
4. | ALA3832789 | F | AntiLeishmania activity L. infantum (macrophages) IC50 (uM) | Leishmania infantum | 65 | ALA3832761 | organism-based format | MMV Pathogen Box | |
5. | ALA3832790 | F | AntiLeishmania activity L. donovani (axenic) IC50 (uM) | Leishmania donovani | 14 | ALA3832761 | organism-based format | MMV Pathogen Box | |
6. | ALA3832791 | F | AntiLeishmania activity L. donovani (macrophages) IC50 (uM) | Leishmania donovani | 14 | ALA3832761 | organism-based format | MMV Pathogen Box | |
7. | ALA3832792 | F | AntiLeishmania activity Toxicity on infected PMM (uM) | Leishmania | 14 | ALA3832761 | organism-based format | MMV Pathogen Box | |
8. | ALA3832830 | F | Cytotoxicity data HepG2 CC20 (uM) | 172 | ALA3832761 | cell-based format | MMV Pathogen Box | ||
9. | ALA3832841 | F | L6 CC50 (uM) Cytotoxicity | 14 | ALA3832761 | cell-based format | MMV Pathogen Box | ||
10. | ALA3832842 | F | MRC5 CC50 (uM) Cytotoxicity | 77 | ALA3832761 | cell-based format | MMV Pathogen Box | ||
11. | ALA3832843 | F | PMM CC50 (uM) Cytotoxicity | 65 | ALA3832761 | cell-based format | MMV Pathogen Box | ||
12. | ALA3987222 | B | Compound was evaluated for the inhibition of human FECH at 10uM | Homo sapiens | 400 | ALA3987221 | single protein format | MMV Pathogen Box | |
13. | ALA3987223 | B | Compound was evaluated for the inhibition of human HMBS at 100uM | Homo sapiens | 400 | ALA3987221 | assay format | MMV Pathogen Box | |
14. | ALA4369188 | F | Antitrypanosomal activity against Trypanosoma brucei brucei 427 bloodstream forms after 48 hrs by resazurin dye based fluorescence assay | Trypanosoma brucei brucei | 69 | ALA4368861 | organism-based format | Scientific Literature | |
15. | ALA4369189 | F | Antitrypanosomal activity against Trypanosoma brucei brucei by pathogen box screening based assay | Trypanosoma brucei brucei | 34 | ALA4368861 | organism-based format | Scientific Literature | |
16. | ALA4369190 | F | Antitrypanosomal activity against Trypanosoma brucei brucei 427 bloodstream forms assessed as parasite viability at 10 uM after 24 hrs by resazurin dye based fluorescence assay relative to control | Trypanosoma brucei brucei | 69 | ALA4368861 | organism-based format | Scientific Literature | |
17. | ALA4369191 | F | Antitrypanosomal activity against Trypanosoma brucei brucei 427 bloodstream forms after 24 hrs by resazurin dye based fluorescence assay | Trypanosoma brucei brucei | 70 | ALA4368861 | organism-based format | Scientific Literature | |
18. | ALA4369192 | A | Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by resazurin dye based fluorescence assay | Homo sapiens | 70 | ALA4368861 | cell-based format | Scientific Literature | |
19. | ALA4513102 | F | Growth inhibiting activity of Naegleria gruberi in vitro | Naegleria gruberi | 399 | ALA4513101 | organism-based format | MMV Pathogen Box |