# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4417891 | F | Growth inhibition of BRCA2-deficient human Capan1 cells at 2.5 to 10 uM following media refreshment every 3 days and measured on day 10 by CellTiter-Glo assay | Homo sapiens | 6 | ALA4417629 | cell-based format | Patent Bioactivity Data | |
2. | ALA4417892 | F | Growth inhibition of BRCA1-deficient human UWB1.289 cells at 2.5 to 10 uM following media refreshment every 3 days and measured on day 10 by CellTiter-Glo assay | Homo sapiens | 6 | ALA4417629 | assay format | Patent Bioactivity Data | |
3. | ALA4417893 | B | Inhibition of RAD51 (unknown origin) assessed as inhibition of DNA pairing by measuring D-loop formation between [32P]-ssDNA and homologous supercoiled pUC19 DNA at 30 uM incubated for 15 mins by gel electrophoresis method relative to control | Homo sapiens | 17 | ALA4417629 | single protein format | Patent Bioactivity Data | |
4. | ALA4417894 | B | Inhibition of RAD52 (unknown origin) assessed as effect on ssDNA annealing using ssDNA oligonucleotide by fluorescence-quenching assay | Homo sapiens | 17 | ALA4417629 | single protein format | Patent Bioactivity Data | |
5. | ALA4417895 | B | Inhibition of RAD52 (unknown origin) assessed as inhibition of DNA pairing using [32P]-ssDNA by measuring D-loop formation incubated for 15 mins by gel electrophoresis method | Homo sapiens | 17 | ALA4417629 | single protein format | Patent Bioactivity Data | |
6. | ALA4417896 | B | Inhibition of RAD51 (unknown origin) assessed as inhibition of DNA pairing by measuring D-loop formation between [32P]-ssDNA and homologous supercoiled pUC19 DNA at 10 times RAD52 IC50 incubated for 15 mins by gel electrophoresis method relative to control | Homo sapiens | 17 | ALA4417629 | single protein format | Patent Bioactivity Data |