| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA678768 | F | Agonism at turkey erythrocyte P2Y receptor. | Meleagris gallopavo | 22 | assay format | Scientific Literature | ||
| 2. | ALA688417 | F | Tested for contraction of guinea pig isolated urinary bladder detrusor muscle by 1 uM alpha,beta-MeATP at 37 degree C; Not active | Cavia porcellus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA688420 | F | Tested for contraction of guinea pig vas deferens at 37 degree C; Not active | Cavia porcellus | 6 | organism-based format | Scientific Literature | ||
| 4. | ALA688426 | F | Tested for relaxation of carbachol-contracted guinea pig taenia coli at 37 degree C; Potency equal to ATP | Cavia porcellus | 4 | organism-based format | Scientific Literature | ||
| 5. | ALA766763 | B | Activation of Purinoceptor P2Y1-mediated phospholipase C in turkey erythrocyte membranes | Meleagris gallopavo | 15 | cell membrane format | Scientific Literature | ||
| 6. | ALA768185 | F | Tested for relaxation of carbachol-contracted rabbit mesenteric artery at 37 degree C; Not active | Oryctolagus cuniculus | 2 | organism-based format | Scientific Literature | ||
| 7. | ALA768187 | F | Tested for relaxation of carbachol-contracted rabbit mesenteric artery at 37 degree C; Significantly less potent than 2MeSATP | Oryctolagus cuniculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA773950 | F | Tested for contraction of rabbit saphenous artery produced by 1 uM alpha,beta-MeATP at 37 degree C; Not active | Oryctolagus cuniculus | 11 | organism-based format | Scientific Literature | ||
| 9. | ALA3364109 | A | Stability assessed as human NTPDase1-mediated compound hydrolysis | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 10. | ALA3364110 | A | Stability assessed as human NTPDase2-mediated compound hydrolysis | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 11. | ALA3364111 | A | Stability assessed as human NTPDase3-mediated compound hydrolysis | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 12. | ALA3364112 | A | Stability assessed as human NTPDase4-mediated compound hydrolysis | Homo sapiens | 9 | single protein format | Scientific Literature | ||
| 13. | ALA4338389 | A | Substrate activity at recombinant full-length human CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of GTP by HPLC-UV analysis | Homo sapiens | 41 | assay format | Scientific Literature | ||
| 14. | ALA4338390 | A | Substrate activity at recombinant full-length mouse CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of GTP by HPLC-UV analysis | Mus musculus | 41 | assay format | Scientific Literature | ||
| 15. | ALA4338391 | A | Substrate activity at recombinant full-length chicken CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of GTP by HPLC-UV analysis | Gallus gallus | 41 | assay format | Scientific Literature | ||
| 16. | ALA4338392 | A | Substrate activity at recombinant full-length human CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of ATP by HPLC-UV analysis | Homo sapiens | 41 | assay format | Scientific Literature | ||
| 17. | ALA4338393 | A | Substrate activity at recombinant full-length mouse CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of ATP by HPLC-UV analysis | Mus musculus | 41 | assay format | Scientific Literature | ||
| 18. | ALA4338394 | A | Substrate activity at recombinant full-length chicken CGAS expressed in Escherichia coli BL21 (DE3) assessed as cyclic dinucleotide formation by measuring reaction conversion at 1 mM incubated for 16 hrs in presence of ATP by HPLC-UV analysis | Gallus gallus | 41 | assay format | Scientific Literature | ||
| 19. | ALA5126047 | B | Agonist activity at human P2X1R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 20. | ALA5126048 | B | Agonist activity at human P2X2R expressing CHO cells assessed as reduction in intracellular Ca2+ influx pretreated with Fluo-4 for 1 hr followed by compound addition and further incubated for 30 mins in presence of ATP by multimode plate reader analysis | Homo sapiens | 16 | cell-based format | Scientific Literature |
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