# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1697778 | A | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans | Homo sapiens | 944 | ALA1697731 | tissue-based format | Scientific Literature | |
2. | ALA1697779 | A | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents | Rodentia | 944 | ALA1697731 | tissue-based format | Scientific Literature | |
3. | ALA1697780 | A | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents | 944 | ALA1697731 | tissue-based format | Scientific Literature | ||
4. | ALA3380976 | B | Binding affinity to HIV-1 TAR RNA by Tat-TAR fluorimetric competition assay | Human immunodeficiency virus 1 | 29 | ALA3352792 | nucleic acid format | Scientific Literature | |
5. | ALA4303805 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | ALA4303101 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
6. | ALA4400160 | B | Induction of recombinant human C5a destabilization assessed as intrinsically disordered structure at 2 to 4 M by circular dichroism analysis | Homo sapiens | 1 | ALA4396950 | single protein format | Scientific Literature | |
7. | ALA4400162 | B | Induction of recombinant human C5a destabilization assessed as protein unfolding at 6 M by circular dichroism analysis | Homo sapiens | 1 | ALA4396950 | single protein format | Scientific Literature | |
8. | ALA4400172 | B | Induction of recombinant human C5a destabilization assessed as protein unfolding at 6 M after 1 hr by fluorescence analysis | Homo sapiens | 1 | ALA4396950 | single protein format | Scientific Literature | |
9. | ALA4400174 | B | Induction of recombinant human C5a destabilization assessed as protein unfolding at 6 M incubated for overnight by fluorescence analysis | Homo sapiens | 1 | ALA4396950 | single protein format | Scientific Literature | |
10. | ALA4405882 | B | Binding affinity to full length human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) assessed as melting temperature heated up to 95 degree C for 3 mins by nano differential scanning fluorimetry analysis | Homo sapiens | 1 | ALA4402594 | assay format | Scientific Literature | |
11. | ALA4405886 | B | Binding affinity to truncated human N-terminal His6-tagged LDH-H expressed in Escherichia coli Rosetta (DE3) assessed as melting temperature heated up to 95 degree C for 3 mins by nano differential scanning fluorimetry analysis | Homo sapiens | 1 | ALA4402594 | assay format | Scientific Literature | |
12. | ALA4405887 | B | Binding affinity to full length human N-terminal His6-tagged LDH-H T2A mutant expressed in Escherichia coli Rosetta (DE3) assessed as melting temperature heated up to 95 degree C for 3 mins by nano differential scanning fluorimetry analysis | Homo sapiens | 1 | ALA4402594 | assay format | Scientific Literature | |
13. | ALA4405888 | B | Binding affinity to full length human N-terminal His6-tagged LDH-H L3A mutant expressed in Escherichia coli Rosetta (DE3) assessed as melting temperature heated up to 95 degree C for 3 mins by nano differential scanning fluorimetry analysis | Homo sapiens | 1 | ALA4402594 | assay format | Scientific Literature | |
14. | ALA4405889 | B | Binding affinity to full length human N-terminal His6-tagged LDH-H K4A mutant expressed in Escherichia coli Rosetta (DE3) assessed as melting temperature heated up to 95 degree C for 3 mins by nano differential scanning fluorimetry analysis | Homo sapiens | 1 | ALA4402594 | assay format | Scientific Literature | |
15. | ALA4405890 | B | Binding affinity to full length human N-terminal His6-tagged LDH-H E5A mutant expressed in Escherichia coli Rosetta (DE3) assessed as melting temperature heated up to 95 degree C for 3 mins by nano differential scanning fluorimetry analysis | Homo sapiens | 1 | ALA4402594 | assay format | Scientific Literature | |
16. | ALA4405891 | B | Binding affinity to full length human N-terminal His6-tagged LDH-H K6A mutant expressed in Escherichia coli Rosetta (DE3) assessed as melting temperature heated up to 95 degree C for 3 mins by nano differential scanning fluorimetry analysis | Homo sapiens | 1 | ALA4402594 | assay format | Scientific Literature | |
17. | ALA4405892 | B | Binding affinity to full length human N-terminal His6-tagged LDH-H L7A mutant expressed in Escherichia coli Rosetta (DE3) assessed as melting temperature heated up to 95 degree C for 3 mins by nano differential scanning fluorimetry analysis | Homo sapiens | 1 | ALA4402594 | assay format | Scientific Literature | |
18. | ALA4405893 | B | Binding affinity to full length human N-terminal His6-tagged LDH-H I8A mutant expressed in Escherichia coli Rosetta (DE3) assessed as melting temperature heated up to 95 degree C for 3 mins by nano differential scanning fluorimetry analysis | Homo sapiens | 1 | ALA4402594 | assay format | Scientific Literature | |
19. | ALA4405894 | B | Binding affinity to full length human N-terminal His6-tagged LDH-H L3A mutant expressed in Escherichia coli Rosetta (DE3) assessed as change in melting temperature heated up to 95 degree C for 3 mins by nano differential scanning fluorimetry analysis | Homo sapiens | 1 | ALA4402594 | assay format | Scientific Literature | |
20. | ALA4405895 | B | Binding affinity to full length human N-terminal His6-tagged LDH-H I8A mutant expressed in Escherichia coli Rosetta (DE3) assessed as changed in melting temperature heated up to 95 degree C for 3 mins by nano differential scanning fluorimetry analysis | Homo sapiens | 1 | ALA4402594 | assay format | Scientific Literature |