1. ALA836095 F Inhibitory concentration against human immunodeficiency virus isolates utilizing C-C chemokine receptor type 5 for cell entry Homo sapiens 1 ALA1142687 assay format Scientific Literature 2. ALA826899 F Mean decrease in viral load in humans after administration of 25 mg once a day; expressed as log 10 reduction Homo sapiens 1 ALA1142687 cell-based format Scientific Literature 3. ALA874810 F Mean decrease in viral load in humans after administration of 100 mg twice a day; expressed as log10 reduction Homo sapiens 1 ALA1142687 cell-based format Scientific Literature 4. ALA906899 B Inhibition of [3H]dofetilide binding to HERG expressed in HEK293 cells at 300 nM Homo sapiens 6 ALA1148680 cell-based format Scientific Literature 5. ALA908640 F Antiviral activity against HIV BaL in PM1 cell Human immunodeficiency virus 6 ALA1148680 organism-based format Scientific Literature 6. ALA908641 P Distribution coefficient, log D of the compound 4 ALA1148680 small-molecule physicochemical format Scientific Literature 7. ALA855890 B Inhibition of [3H]dofetilide binding to HERG expressed in HEK293 cells at 1000 nM Homo sapiens 1 ALA1148680 cell-based format Scientific Literature 8. ALA949218 F Antiviral activity against HIV1 JRCSF by viral entry assay Human immunodeficiency virus 1 24 ALA1143192 organism-based format Scientific Literature 9. ALA949219 F Antiviral activity against HIV1 ASM80 by viral entry assay Human immunodeficiency virus 1 24 ALA1143192 organism-based format Scientific Literature 10. ALA949220 F Antiviral activity against HIV1 BaL by viral entry assay Human immunodeficiency virus 1 24 ALA1143192 organism-based format Scientific Literature 11. ALA949221 F Antiviral activity against HIV1 97-ZA-003 by viral entry assay Human immunodeficiency virus 1 24 ALA1143192 organism-based format Scientific Literature 12. ALA949222 F Antiviral activity against HIV1 RU570 by viral entry assay Human immunodeficiency virus 1 24 ALA1143192 organism-based format Scientific Literature 13. ALA1034062 B Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 expressing CHO cells by cell-cell fusion assay Homo sapiens 35 ALA1152728 cell-based format Scientific Literature 14. ALA1034063 F Antiviral activity against HIV1 Bal infected in human PM1 cells assessed as inhibition of viral replication Human immunodeficiency virus 1 10 ALA1152728 organism-based format Scientific Literature 15. ALA1034064 P Lipophilicity, log D at pH 7.4 12 ALA1152728 small-molecule physicochemical format Scientific Literature 16. ALA1034065 A Metabolic stability in human liver microsomes assessed as clearance measured per mg of protein Homo sapiens 12 ALA1152728 microsome format Scientific Literature 17. ALA1034066 P Dissociation constant, pKa of the compound 5 ALA1152728 small-molecule physicochemical format Scientific Literature 18. ALA1034068 B Displacement of [3H]dofetilide from human ERG expressed in HEK293 cells at 300 nM Homo sapiens 2 ALA1152728 cell-based format Scientific Literature 19. ALA1019461 B Antagonist activity at human recombinant CCR5 expressed in human HeLa-P4 cells assessed as inhibition of human HeLa-P4 cells binding to HIV1 gp160 expressing CHO cells by cell-cell fusion assay Homo sapiens 23 ALA1152883 cell-based format Scientific Literature 20. ALA1019462 P Lipophilicity, log D at pH 7.4 12 ALA1152883 small-molecule physicochemical format Scientific Literature