# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA729340 | B | Inhibitory activity against Monoamine Oxidase B of Bovine liver in competitive inhibition assay at 25 degree C (pH=7.4) | Bos taurus | 11 | ALA1124175 | assay format | Scientific Literature | |
2. | ALA729493 | B | Competitive inhibition of Rat liver Monoamine Oxidase B at 37 degree C (pH= 7.4) | 3 | ALA1124175 | assay format | Scientific Literature | ||
3. | ALA792954 | F | Effect on the spontaneous locomotor activity of rats at 0-15 min upon ip administration of the compounds at a dose of 1 mg/kg | Rattus norvegicus | 1 | ALA1125865 | organism-based format | Scientific Literature | |
4. | ALA793124 | F | Effect on the spontaneous locomotor activity of rats at 0-60 min upon ip administration of the compounds at a dose of 100 mg/kg. | Rattus norvegicus | 2 | ALA1125865 | organism-based format | Scientific Literature | |
5. | ALA804959 | B | Binding affinity towards sigma opioid receptor in guinea pig cerebral homogenate using [3H]DTG as radioligand | Cavia porcellus | 20 | ALA1125624 | assay format | Scientific Literature | |
6. | ALA876466 | P | Lipophilicity determined as logarithm of the partition coefficient in the alkane/water system | 181 | ALA1143634 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA1614670 | A | Volume of distribution at steady state in human after iv administration | Homo sapiens | 667 | ALA1614632 | organism-based format | Scientific Literature | |
8. | ALA1614671 | A | Clearance in human after iv administration | Homo sapiens | 667 | ALA1614632 | organism-based format | Scientific Literature | |
9. | ALA1614672 | A | Fraction unbound in human after iv administration | Homo sapiens | 554 | ALA1614632 | organism-based format | Scientific Literature | |
10. | ALA1614673 | A | Mean residence time in human after iv administration | Homo sapiens | 667 | ALA1614632 | organism-based format | Scientific Literature | |
11. | ALA1614674 | A | Half life in human after iv administration | Homo sapiens | 667 | ALA1614632 | organism-based format | Scientific Literature | |
12. | ALA1697778 | A | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in humans | Homo sapiens | 944 | ALA1697731 | tissue-based format | Scientific Literature | |
13. | ALA1697779 | A | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in rodents | Rodentia | 944 | ALA1697731 | tissue-based format | Scientific Literature | |
14. | ALA1697780 | A | Literature-mined compound from Fourches et al multi-species drug-induced liver injury (DILI) dataset, effect in non-rodents | 944 | ALA1697731 | tissue-based format | Scientific Literature | ||
15. | ALA1909307 | A | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for bilirubinemia | 888 | ALA1909294 | tissue-based format | Scientific Literature | ||
16. | ALA1909308 | A | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholecystitis | 888 | ALA1909294 | tissue-based format | Scientific Literature | ||
17. | ALA1909309 | A | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cholelithiasis | 888 | ALA1909294 | tissue-based format | Scientific Literature | ||
18. | ALA1909310 | A | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for cirrhosis | 888 | ALA1909294 | tissue-based format | Scientific Literature | ||
19. | ALA1909311 | A | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for elevated liver function tests | 888 | ALA1909294 | tissue-based format | Scientific Literature | ||
20. | ALA1909312 | A | Drug Induced Liver Injury Prediction System (DILIps) training set; hepatic side effect (HepSE) score for hepatic failure | 888 | ALA1909294 | tissue-based format | Scientific Literature |