# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1212031 | Binding | Inhibition of GTPase activity of Cdc42 | 3 | ALA1208766 | single protein format | Scientific Literature | ||
2. | ALA1212033 | Binding | Inhibition of GTPase activity of Dynamin 1 | 17 | ALA1208766 | single protein format | Scientific Literature | ||
3. | ALA1212034 | Functional | Inhibition of transferrin uptake in african green monkey COS7 cells by microscopic TexasRed imaging | Chlorocebus aethiops | 4 | ALA1208766 | cell-based format | Scientific Literature | |
4. | ALA1212035 | Binding | Inhibition of GTPase activity of human mitochondrial Drp1 expressed in Escherichia coli BL-21 | Homo sapiens | 3 | ALA1208766 | assay format | Scientific Literature | |
5. | ALA1212036 | Binding | Inhibition of dynamin 1 mediated membrane fission in african green monkey Cos7 cells transfected with mRFP-LCa at 10 uM by total internal reflection fluorescence microscopy | Chlorocebus aethiops | 3 | ALA1208766 | cell-based format | Scientific Literature | |
6. | ALA4303805 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | ALA4303101 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
7. | ALA4421892 | Binding | Inhibition of full-length native sheep brain dynamin 1 assessed as reduction in PS liposomes-induced GTPase activity | Ovis aries | 3 | ALA4421721 | assay format | Patent Bioactivity Data | |
8. | ALA4421894 | Binding | Ring stabilizer activity at full-length native sheep brain dynamin 1 assessed as stimulation of GTPase activity in absence of PS liposomes | Ovis aries | 7 | ALA4421721 | assay format | Patent Bioactivity Data | |
9. | ALA4421899 | Binding | Inhibition of Dynamin-2 in human lymphoblasts assessed as accumulation of clathrin coated pits at the plasma membrane incubated for 30 mins by electron microscopic analysis | Homo sapiens | 1 | ALA4421721 | assay format | Patent Bioactivity Data | |
10. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
11. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
12. | ALA4808149 | Binding | Enzymatic assay of human HDAC6 with commercial peptide substrate | Homo sapiens | 5,603 | ALA4808148 | single protein format | Fraunhofer HDAC6 | |
13. | ALA4808150 | Binding | Enzymatic assay of human HDAC6 with custom peptide substrate | Homo sapiens | 5,603 | ALA4808148 | single protein format | Fraunhofer HDAC6 |