# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1220164 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 30 uM by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 2 | ALA1212700 | assay format | Scientific Literature | |
2. | ALA1220168 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 1 | ALA1212700 | assay format | Scientific Literature | |
3. | ALA1220169 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid polymerization at 30 uM in presence of 5 mg/ml BSA by thioflavin T fluorescence assay relative to untreated control | Saccharomyces cerevisiae | 2 | ALA1212700 | assay format | Scientific Literature | |
4. | ALA1220173 | P | Inhibition of dynamic light scattering at 2 uM by thioflavin T fluorescence assay relative to untreated control | 1 | ALA1212700 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA1220174 | P | Inhibition of dynamic light scattering at 20 uM by thioflavin T fluorescence assay relative to untreated control | 1 | ALA1212700 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA1220176 | B | Inhibition of mouse prion protein (89-230) assessed as inhibition of amyloid polymerization at 50 uM by thioflavin T fluorescence assay relative to untreated control | Mus musculus | 8 | ALA1212700 | assay format | Scientific Literature | |
7. | ALA1220297 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as coating of prion protein with colonial particles at 100 uM by transmission electron microscopy | Saccharomyces cerevisiae | 1 | ALA1212700 | assay format | Scientific Literature | |
8. | ALA1220299 | B | Inhibition of polyhistidine tagged yeast prion protein Sup35 expressed in Escherichia coli BL21 (DE3) assessed as inhibition of fiber formation at 100 uM by transmission electron microscopy | Saccharomyces cerevisiae | 1 | ALA1212700 | assay format | Scientific Literature | |
9. | ALA1220301 | B | Inhibition of yeast prion protein Sup35 infection of PSI yeast spheroplast cells at 200 uM | Saccharomyces cerevisiae | 6 | ALA1212700 | assay format | Scientific Literature | |
10. | ALA1220303 | B | Inhibition of yeast prion protein Sup35 infection of PSI yeast spheroplast cells | Saccharomyces cerevisiae | 1 | ALA1212700 | assay format | Scientific Literature |