# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1221022 | B | Inhibition of wild type Bacteroides thetaiotaomicron beta-mannosidase 2A expressed in Escherichia coli BL21 (DE3) at 37 degC and Ph 5.6 by 2,4-dinitrophenolate release assay | Bacteroides thetaiotaomicron | 25 | ALA1212704 | assay format | Scientific Literature | |
2. | ALA3618918 | B | Inhibition of human pancreatic alpha-amylase assessed as hydrolysis of G3F by Dixon plot analysis | Homo sapiens | 3 | ALA3616379 | single protein format | Scientific Literature | |
3. | ALA3788466 | B | Inhibition of almond beta glucosidase | Prunus dulcis | 14 | ALA3784998 | assay format | Scientific Literature | |
4. | ALA3788467 | B | Pharmacological chaperone activity at beta-glucocerebrosidase N370S mutant in Gaucher disease patient-derived lymphoblasts with GCase N370S mutant assessed as increase in enzyme activity at 10 uM after 3 days by fluorimetric analysis relative to control | Homo sapiens | 1 | ALA3784998 | single protein format | Scientific Literature | |
5. | ALA3788468 | B | Inhibition of Saccharomyces cerevisiae alpha glucosidase | Saccharomyces cerevisiae | 14 | ALA3784998 | single protein format | Scientific Literature | |
6. | ALA3788469 | B | Inhibition of Escherichia coli beta-galactosidase | Escherichia coli | 14 | ALA3784998 | single protein format | Scientific Literature | |
7. | ALA3788470 | B | Inhibition of green coffee bean alpha-galactosidase | Coffea arabica | 14 | ALA3784998 | single protein format | Scientific Literature | |
8. | ALA3788471 | B | Inhibition of human recombinant imiglucerase using 4-MU-beta-D-Glu as substrate at pH 5.2 after 30 mins by fluorometric analysis | Homo sapiens | 14 | ALA3784998 | single protein format | Scientific Literature | |
9. | ALA3788472 | B | Inhibition of human recombinant imiglucerase using 4-MU-beta-D-Glu as substrate at pH 7.0 after 30 mins by fluorometric analysis | Homo sapiens | 14 | ALA3784998 | single protein format | Scientific Literature | |
10. | ALA3788473 | B | Competitive inhibition of human recombinant imiglucerase using 4-MU-beta-D-Glu as substrate at pH 5.2 after 30 mins by fluorometry based Lineweaver-Burk plot analysis | Homo sapiens | 14 | ALA3784998 | single protein format | Scientific Literature | |
11. | ALA3788474 | B | Pharmacological chaperone activity at beta-glucocerebrosidase N370S mutant in Gaucher disease patient-derived lymphoblasts with GCase N370S mutant assessed as increase in enzyme activity at 3.125 to 100 uM after 3 days by fluorimetric analysis relative to control | Homo sapiens | 14 | ALA3784998 | single protein format | Scientific Literature | |
12. | ALA3790453 | A | Cytotoxicity against wild type human CCC-ESF1 cells at 100 uM after 24 hrs by MTT assay | Homo sapiens | 14 | ALA3784998 | cell-based format | Scientific Literature |