# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1219355 | B | Inhibition of spleen tyrosine kinase in rat RBL-2H3 cells assessed as inhibition of IgE-induced degranulation after 1 hr by beta-hexosaminidase release assay | Rattus norvegicus | 2 | ALA1212882 | cell-based format | Scientific Literature | |
2. | ALA1219357 | B | Inhibition of spleen tyrosine kinase in rat RBL-2H3 cells assessed as inhibition of IgE-induced increase of intracellular calcium level at 50 uM after 30 mins by FLIPR assay | Rattus norvegicus | 2 | ALA1212882 | cell-based format | Scientific Literature | |
3. | ALA1219358 | B | Inhibition of spleen tyrosine kinase in rat RBL-2H3 cells assessed as inhibition of IgE-induced increase of ROS level at 50 uM after 30 mins by FLIPR assay | Rattus norvegicus | 2 | ALA1212882 | cell-based format | Scientific Literature | |
4. | ALA1219359 | B | Inhibition of spleen tyrosine kinase in rat RBL-2H3 cells assessed as inhibition of IgE-induced upregulation of phospholipase Cgamma1 level at 50 uM after 30 mins by Western blotting | Rattus norvegicus | 2 | ALA1212882 | cell-based format | Scientific Literature | |
5. | ALA1219360 | B | Inhibition of spleen tyrosine kinase in rat RBL-2H3 cells assessed as inhibition of IgE-induced upregulation of phospholipase 2 level at 50 uM after 30 mins by Western blotting | Rattus norvegicus | 2 | ALA1212882 | cell-based format | Scientific Literature | |
6. | ALA1219361 | B | Inhibition of spleen tyrosine kinase in rat RBL-2H3 cells assessed as inhibition of IgE-induced upregulation of Lyn level at 50 uM after 30 mins by Western blotting | Rattus norvegicus | 2 | ALA1212882 | cell-based format | Scientific Literature | |
7. | ALA1219362 | B | Inhibition of spleen tyrosine kinase in rat RBL-2H3 cells assessed as inhibition of IgE-induced upregulation of PI3K/Akt level at 50 uM after 30 mins by Western blotting | Rattus norvegicus | 1 | ALA1212882 | cell-based format | Scientific Literature | |
8. | ALA1219363 | B | Inhibition of spleen tyrosine kinase in rat RBL-2H3 cells assessed as inhibition of IgE-induced upregulation of ERK1/2 level at 50 uM after 30 mins by Western blotting | Rattus norvegicus | 1 | ALA1212882 | cell-based format | Scientific Literature | |
9. | ALA1219364 | B | Inhibition of spleen tyrosine kinase in rat RBL-2H3 cells assessed as inhibition of IgE-induced upregulation of JNK level at 50 uM after 30 mins by Western blotting | Rattus norvegicus | 1 | ALA1212882 | cell-based format | Scientific Literature | |
10. | ALA1219365 | B | Inhibition of spleen tyrosine kinase in rat RBL-2H3 cells assessed as inhibition of IgE-induced upregulation of p38 level at 50 uM after 30 mins by Western blotting | Rattus norvegicus | 1 | ALA1212882 | cell-based format | Scientific Literature | |
11. | ALA1219366 | B | Inhibition of spleen tyrosine kinase in rat RBL-2H3 cells assessed as inhibition of IgE-induced upregulation of cPLA2 level at 50 uM after 30 mins by Western blotting | Rattus norvegicus | 1 | ALA1212882 | cell-based format | Scientific Literature |