# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1219909 | F | Antagonist activity at rat recombinant NR1-NR2A receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp electrophysiology | Rattus norvegicus | 94 | ALA1212913 | cell-based format | Scientific Literature | |
2. | ALA1219910 | B | Selectivity ratio of IC50 for rat recombinant GLuR1 to IC50 for rat recombinant NR1-NR2D receptor | Rattus norvegicus | 93 | ALA1212913 | assay format | Scientific Literature | |
3. | ALA1219911 | F | Antagonist activity at rat recombinant NR1-NR2B receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp electrophysiology | Rattus norvegicus | 94 | ALA1212913 | cell-based format | Scientific Literature | |
4. | ALA1219912 | F | Antagonist activity at rat recombinant NR1-NR2C receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp electrophysiology | Rattus norvegicus | 94 | ALA1212913 | cell-based format | Scientific Literature | |
5. | ALA1219913 | F | Antagonist activity at rat recombinant NR1-NR2D receptor expressed in Xenopus oocytes at holding potential of -40mV by two-electrode voltage-clamp electrophysiology | Rattus norvegicus | 94 | ALA1212913 | cell-based format | Scientific Literature | |
6. | ALA1219914 | F | Antagonist activity at rat recombinant GLuR1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced current by two-electrode voltage-clamp electrophysiology | Rattus norvegicus | 94 | ALA1212913 | cell-based format | Scientific Literature | |
7. | ALA1219916 | B | Selectivity ratio of IC50 for rat recombinant NR1-NR2A receptor to IC50 for rat recombinant NR1-NR2D receptor | Rattus norvegicus | 93 | ALA1212913 | assay format | Scientific Literature | |
8. | ALA1219917 | B | Selectivity ratio of IC50 for rat recombinant NR1-NR2A/NR1-NR2B receptor to IC50 for rat recombinant NR1-NR2C/NR1-NR2D receptor | Rattus norvegicus | 94 | ALA1212913 | assay format | Scientific Literature | |
9. | ALA4309003 | B | Negative allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 7 | ALA4308825 | cell-based format | Scientific Literature | |
10. | ALA4309004 | B | Negative allosteric modulation of GluN2B receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 9 | ALA4308825 | cell-based format | Scientific Literature | |
11. | ALA4309006 | B | Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 10 | ALA4308825 | cell-based format | Scientific Literature | |
12. | ALA4309007 | B | Negative allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced channel current by two electrode voltage clamp method | Homo sapiens | 9 | ALA4308825 | cell-based format | Scientific Literature |