1. ALA1219449 P Aqueous solubility of the compound at pH 4.5 2 small-molecule physicochemical format Scientific Literature 2. ALA1219450 P Aqueous solubility of the compound at pH 6.6 24 small-molecule physicochemical format Scientific Literature 3. ALA1219451 P Aqueous solubility of the compound at pH 7.4 2 small-molecule physicochemical format Scientific Literature 4. ALA1219452 P Aqueous solubility of the compound at pH 9 2 small-molecule physicochemical format Scientific Literature 5. ALA1219453 B Inhibition of recombinant PSGL-1 at 250 uM by surface plasmon resonance assay 42 single protein format Scientific Literature 6. ALA1219455 A Oral bioavailability in Sprague-Dawley rat at 10 mg/kg Rattus norvegicus 15 organism-based format Scientific Literature 7. ALA1219456 A Clearance in Sprague-Dawley rat at 3 mg/kg, iv and 10 mg/kg, po Rattus norvegicus 15 organism-based format Scientific Literature 8. ALA1219457 A Dose normalized AUC in Sprague-Dawley rat measured per mg of plasma at 3 mg/kg, iv and 10 mg/kg, po Rattus norvegicus 15 organism-based format Scientific Literature 9. ALA1219459 F Reduction of leukocytes rolling flux in acute intravital microscopy model of C57B6 mouse cremasteric postcapillary venules at 50 mg/kg, po after 35 mins relative to control Mus musculus 2 organism-based format Scientific Literature 10. ALA1219460 B Binding affinity to recombinant PSGL-1 assessed as saturation transfer difference at 100 uM by NMR analysis 1 single protein format Scientific Literature 11. ALA1219461 P Solubility of the compound in simulated intestinal fluid 1 small-molecule physicochemical format Scientific Literature 12. ALA1219462 P Solubility of the compound in fed simulated intestinal bile salts-lecithin mixture fluid at pH 5.5 1 small-molecule physicochemical format Scientific Literature 13. ALA1219463 P Solubility of the compound in fasted simulated intestinal bile salts-lecithin mixture fluid at pH 6 1 small-molecule physicochemical format Scientific Literature 14. ALA1219464 P Physiological stability of the compound at pH 1 assessed as compound remaining after 4 hrs in presence of 20% acetonitrile 1 small-molecule physicochemical format Scientific Literature 15. ALA1219465 P Physiological stability of the compound at pH 1 assessed as compound remaining after 8 hrs in presence of 20% acetonitrile 1 small-molecule physicochemical format Scientific Literature 16. ALA1219466 P Physiological stability of the compound at pH 1 assessed as compound remaining after 12 hrs in presence of 20% acetonitrile 1 small-molecule physicochemical format Scientific Literature 17. ALA1219467 P Physiological stability of the compound at pH 1 assessed as compound remaining after 16 hrs in presence of 20% acetonitrile 1 small-molecule physicochemical format Scientific Literature 18. ALA1219468 P Physiological stability of the compound at pH 1 assessed as compound remaining after 20 hrs in presence of 20% acetonitrile 1 small-molecule physicochemical format Scientific Literature 19. ALA1219469 P Physiological stability of the compound at pH 1 assessed as compound remaining after 24 hrs in presence of 20% acetonitrile 1 small-molecule physicochemical format Scientific Literature 20. ALA1219470 P Physiological stability of the compound at pH 4.5 assessed as compound remaining after 4 hrs in presence of 20% acetonitrile 1 small-molecule physicochemical format Scientific Literature