# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1227766 | B | Transactivation of RARalpha in human COS7 cells at 10 uM by luciferase reporter gene assay | Homo sapiens | 4 | ALA1221250 | cell-based format | Scientific Literature | |
2. | ALA1227768 | F | Agonist activity at RXRalpha by luciferase reporter gene assay | 3 | ALA1221250 | assay format | Scientific Literature | ||
3. | ALA1227769 | B | Transactivation of PPARgamma | 3 | ALA1221250 | single protein format | Scientific Literature | ||
4. | ALA1227770 | B | Transactivation of PPARgamma/RXRalpha heterodimer | 3 | ALA1221250 | protein complex format | Scientific Literature | ||
5. | ALA1227771 | B | Transactivation of LXRalpha | 3 | ALA1221250 | single protein format | Scientific Literature | ||
6. | ALA1227772 | B | Transactivation of LXRalpha/RXRalpha | 3 | ALA1221250 | protein complex format | Scientific Literature | ||
7. | ALA1696021 | F | Agonist activity at RXRalpha transfected in human COS1 cells after 18 hrs by luciferase reporter gene transactivation assay | 15 | ALA1687703 | cell-based format | Scientific Literature | ||
8. | ALA1696022 | F | Agonist activity at RXRalpha transfected in human COS1 cells at 1 uM after 18 hrs by luciferase reporter gene transactivation assay relative to LGD1069 | 15 | ALA1687703 | cell-based format | Scientific Literature | ||
9. | ALA1696023 | F | Agonist activity at PPARgamma transfected in human COS1 cells after 18 hrs by luciferase reporter gene transactivation assay | 3 | ALA1687703 | cell-based format | Scientific Literature | ||
10. | ALA1696024 | F | Agonist activity at LXRalpha transfected in human COS1 cells after 18 hrs by luciferase reporter gene transactivation assay | 3 | ALA1687703 | cell-based format | Scientific Literature | ||
11. | ALA1696025 | F | Agonist activity at RXRalpha transfected in human COS1 cells at 10'-7 to 10'-6 M after 18 hrs by luciferase reporter gene transactivation assay | 3 | ALA1687703 | cell-based format | Scientific Literature | ||
12. | ALA1696526 | F | Agonist activity at PPARgamma/RXRalpha transfected in human COS1 cells at 10'-7 to 10'-6 M after 18 hrs by luciferase reporter gene transactivation assay | 2 | ALA1687703 | cell-based format | Scientific Literature | ||
13. | ALA2149516 | F | Agonist activity at PPARgamma expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay | Homo sapiens | 3 | ALA2146420 | cell-based format | Scientific Literature | |
14. | ALA2149517 | F | Agonist activity at PPARgamma/RXRalpha expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay | Homo sapiens | 3 | ALA2146420 | cell-based format | Scientific Literature | |
15. | ALA2149518 | F | Agonist activity at LXRalpha expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay | Homo sapiens | 3 | ALA2146420 | cell-based format | Scientific Literature | |
16. | ALA2149519 | F | Agonist activity at LXRalpha/RXRalpha expressed in human Cos1 cells after 18 hrs by SEAP reporter gene assay | Homo sapiens | 3 | ALA2146420 | cell-based format | Scientific Literature | |
17. | ALA2149520 | A | Drug level in ICR mouse serum at 30 mg/kg, po | Mus musculus | 3 | ALA2146420 | organism-based format | Scientific Literature | |
18. | ALA2149521 | T | Toxicity in ICR mouse assessed as increase in body weight at 30 mg/kg/day, po for 7 days relative to vehicle-treated control | Mus musculus | 3 | ALA2146420 | organism-based format | Scientific Literature | |
19. | ALA2149522 | T | Toxicity in ICR mouse assessed as increase in liver weight at 30 mg/kg/day, po for 7 days relative to vehicle-treated control | Mus musculus | 3 | ALA2146420 | organism-based format | Scientific Literature | |
20. | ALA2149950 | T | Toxicity in ICR mouse assessed as increase in serum triglyceride level at 30 mg/kg/day, po for 7 days relative to vehicle-treated control | Mus musculus | 2 | ALA2146420 | organism-based format | Scientific Literature |