# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1228350 | F | Antiproliferative activity against human HeLa cells assessed as incorporation of [3H]thymidine in nuclear DNA at 2.5 uM after 24 hrs by scintillation counting | Homo sapiens | 7 | ALA1221230 | cell-based format | Scientific Literature | |
2. | ALA1228351 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as incorporation of [3H]thymidine in nuclear DNA at 2.5 uM after 24 hrs by scintillation counting | Homo sapiens | 7 | ALA1221230 | cell-based format | Scientific Literature | |
3. | ALA1228352 | F | Antiproliferative activity against human Jurkat cells assessed as incorporation of [3H]thymidine in nuclear DNA at 2.5 uM after 24 hrs by scintillation counting | Homo sapiens | 7 | ALA1221230 | cell-based format | Scientific Literature | |
4. | ALA1228353 | F | Inhibition of protein synthesis in human HeLa cells assessed as [35S]cysteine/methionine utilization after 2 hrs by scintillation spectroscopy | Homo sapiens | 8 | ALA1221230 | cell-based format | Scientific Literature | |
5. | ALA1228354 | F | Inhibition of transcriptional activity in human HeLa cells assessed as [3H]uridine utilization after 2 hrs by scintillation counting | Homo sapiens | 6 | ALA1221230 | cell-based format | Scientific Literature | |
6. | ALA1228357 | F | Effect on polyribosome profiling assessed as accumulation of 80S ribosomes after 15 mins by scintillation spectroscopy | 2 | ALA1221230 | assay format | Scientific Literature | ||
7. | ALA1228358 | F | Inhibition of translational activity in rabbit reticulocyte assessed as occurrence of ribosomal arrest at start codon at 200 uM by toeprinting assay | Oryctolagus cuniculus | 1 | ALA1221230 | assay format | Scientific Literature | |
8. | ALA1228361 | B | Inhibition of elF4A-mediated renilla luciferase translational activity at 0.02 to 5 uM in presence of EMCV IRES element | 1 | ALA1221230 | assay format | Scientific Literature | ||
9. | ALA1228362 | B | Inhibition of elF4A-mediated renilla luciferase translational activity at 0.02 to 5 uM in presence of CrPV IRES element | 1 | ALA1221230 | assay format | Scientific Literature | ||
10. | ALA1228363 | B | Inhibition of eEF2-mediated tRNA translocation assessed as inhibition of polyphenylalanine synthesis at 200 uM after 10 mins by scintillation counting | 1 | ALA1221230 | single protein format | Scientific Literature | ||
11. | ALA1228364 | B | Inhibition of eEF1A-mediated tRNA binding to ternary complex at 200 uM after 10 mins by filtration binding assay | 2 | ALA1221230 | single protein format | Scientific Literature | ||
12. | ALA1228365 | B | Effect on eEF1A-mediated peptidyl transfer assessed as [35S]methionyl-puromycin formation by TLC | 2 | ALA1221230 | single protein format | Scientific Literature | ||
13. | ALA1228366 | B | Inhibition of eEF2-mediated tRNA translocation assessed as inhibition of phenylalanyl puromycin formation | 2 | ALA1221230 | single protein format | Scientific Literature | ||
14. | ALA1228367 | B | Inhibition of eEF2-mediated tRNA translocation assessed as decrease in tripeptide (Met-Phe-Phe) formation by TLC | 2 | ALA1221230 | single protein format | Scientific Literature | ||
15. | ALA1228368 | B | Inhibition of eEF2-mediated tRNA translocation assessed as induction of dipeptide accumulation by TLC | 2 | ALA1221230 | single protein format | Scientific Literature | ||
16. | ALA1228369 | F | Antimicrobial activity against Saccharomyces cerevisiae J407alpha expressing ribosomal protein cyh2 and harboring mutation in rpl28 | Saccharomyces cerevisiae | 2 | ALA1221230 | organism-based format | Scientific Literature | |
17. | ALA1228370 | B | Binding affinity to 60S ribosome E-site by footprinting assay | 2 | ALA1221230 | assay format | Scientific Literature | ||
18. | ALA1228371 | F | Anticancer activity against human Hs 578T cells after 24 hrs by [3H]thymidine incorporation assay | Homo sapiens | 1 | ALA1221230 | cell-based format | Scientific Literature | |
19. | ALA1228372 | F | Anticancer activity against human HCC1937 cells after 24 hrs by [3H]thymidine incorporation assay | Homo sapiens | 1 | ALA1221230 | cell-based format | Scientific Literature | |
20. | ALA1228373 | F | Anticancer activity against human HCC1395 cells after 24 hrs by [3H]thymidine incorporation assay | Homo sapiens | 1 | ALA1221230 | cell-based format | Scientific Literature |