# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1227179 | B | Binding affinity to factor 10a | 55 | single protein format | Scientific Literature | |||
2. | ALA1227180 | F | Anticoagulant activity in plasma assessed as concentration required to double prothrombin time | 55 | cell-free format | Scientific Literature | |||
3. | ALA1227181 | P | Lipophilicity, log D of the compound at pH 7.4 | 42 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA1227182 | B | Binding affinity to thrombin | 30 | single protein format | Scientific Literature | |||
5. | ALA1227184 | B | Inhibition of peptidase activity of prothrombinase complex assessed as thrombin production | 4 | assay format | Scientific Literature | |||
6. | ALA1227185 | B | Binding affinity to rabbit factor 10a | Oryctolagus cuniculus | 4 | single protein format | Scientific Literature | ||
7. | ALA1227186 | B | Binding affinity to rat factor 10a | Rattus norvegicus | 4 | single protein format | Scientific Literature | ||
8. | ALA1227187 | F | Ex vivo anticoagulation activity in human whole blood assessed as inhibition of collagen-induced platelet aggregation | Homo sapiens | 4 | tissue-based format | Scientific Literature | ||
9. | ALA1227188 | F | Ex vivo anticoagulation activity in human whole blood assessed as inhibition of J82 cells expressing tissue factor-induced platelet aggregation | Homo sapiens | 4 | tissue-based format | Scientific Literature | ||
10. | ALA1227189 | B | Inhibition of tissue factor/factor 7a | 4 | protein complex format | Scientific Literature | |||
11. | ALA1227190 | B | Inhibition of thrombin | 4 | single protein format | Scientific Literature | |||
12. | ALA1227191 | B | Inhibition of activated protein C | 4 | single protein format | Scientific Literature | |||
13. | ALA1227345 | B | Inhibition of plasmin | 4 | single protein format | Scientific Literature | |||
14. | ALA1227346 | B | Inhibition of kallikrein | 4 | assay format | Scientific Literature | |||
15. | ALA1227347 | A | Fraction unbound in human plasma | Homo sapiens | 4 | cell-free format | Scientific Literature | ||
16. | ALA1227348 | A | Clearance in human microsomes | Homo sapiens | 4 | microsome format | Scientific Literature | ||
17. | ALA1227349 | A | Clearance in human hepatocytes | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
18. | ALA1227350 | B | Inhibition of human ERG | Homo sapiens | 4 | single protein format | Scientific Literature | ||
19. | ALA1227351 | A | Oral bioavailability in rat | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
20. | ALA1227352 | A | Half life in po dosed rat | Rattus norvegicus | 4 | organism-based format | Scientific Literature |