# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1224958 | Binding | Inhibition of human cathepsin L using Z-FR-AMC substrate assessed as inhibition association constant by fluorimetric assay | Homo sapiens | 4 | ALA1221173 | single protein format | Scientific Literature | |
2. | ALA1224959 | Binding | Inhibition of bovine cathepsin B using Z-RR-AMC substrate assessed as inhibition association constant by fluorimetric assay | Bos taurus | 4 | ALA1221173 | single protein format | Scientific Literature | |
3. | ALA1224960 | Binding | Binding affinity to human recombinant cathepsin L assessed as protein labeling at 0.1 to 10 uM after 30 mins using SDS-PAGE and Typhoon laser flatbed canning method | Homo sapiens | 2 | ALA1221173 | single protein format | Scientific Literature | |
4. | ALA1224961 | Binding | Binding affinity to bovine recombinant cathepsin B assessed as protein labeling at 0.1 to 10 uM after 30 mins using SDS-PAGE and Typhoon laser flatbed canning method | Bos taurus | 2 | ALA1221173 | single protein format | Scientific Literature | |
5. | ALA1224962 | Binding | Binding affinity to recombinant cathepsin S assessed as protein labeling at 0.1 to 10 uM after 30 mins using SDS-PAGE and Typhoon laser flatbed canning method | 2 | ALA1221173 | single protein format | Scientific Literature | ||
6. | ALA1224963 | Binding | Binding affinity to recombinant cathepsin X assessed as protein labeling at 0.1 to 10 uM after 30 mins using SDS-PAGE and Typhoon laser flatbed canning method | 2 | ALA1221173 | single protein format | Scientific Literature | ||
7. | ALA1224964 | Binding | Binding affinity to cathepsin B in mouse NIH/3T3 cells assessed as protein labeling at 1 uM after 30 mins using SDS-PAGE and Typhoon laser flatbed canning method | Mus musculus | 2 | ALA1221173 | cell-based format | Scientific Literature | |
8. | ALA1224965 | Binding | Binding affinity to cathepsin L in mouse NIH/3T3 cells assessed as protein labeling at 1 uM after 30 mins using SDS-PAGE and Typhoon laser flatbed canning method | Mus musculus | 2 | ALA1221173 | cell-based format | Scientific Literature | |
9. | ALA1224966 | ADME | Cytotoxicity against mouse NIH/3T3 cells | Mus musculus | 2 | ALA1221173 | cell-based format | Scientific Literature | |
10. | ALA1224967 | Binding | Binding affinity to cathepsin B in mouse NIH/3T3 cells monolayers assessed as protein labeling at 1 uM after 4 to 5 hrs by fluorescence microscopy | Mus musculus | 2 | ALA1221173 | cell-based format | Scientific Literature | |
11. | ALA1224968 | Binding | Binding affinity to cathepsin L in human MCF10A cells grown on reconstituted basement membrane exposed to 1 uM compounds assessed as protein labeling after 3 hrs by confocal fluorescence microscopy | Homo sapiens | 2 | ALA1221173 | cell-based format | Scientific Literature | |
12. | ALA1224969 | Binding | Binding affinity to cathepsin B in human MCF10A cells grown on reconstituted basement membrane exposed to 1 uM compounds assessed as protein labeling after 3 hrs by confocal fluorescence microscopy | Homo sapiens | 2 | ALA1221173 | cell-based format | Scientific Literature |