# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1225070 | B | Inhibition of human huntingtin N548 mutant expressed in rat ST14A cells assessed as decrease in cell death | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
2. | ALA1225071 | F | Inhibition of cell death in rat ST14A cells assessed as cell viability | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
3. | ALA1225072 | A | Cytotoxicity against rat ST14A cells transfected with human htt gene | Rattus norvegicus | 29 | cell-based format | Scientific Literature | ||
4. | ALA1225073 | B | Inhibition of human huntingtin Q103 mutant expressed in rat PC12 cells assessed as decrease in cell death | 29 | cell-based format | Scientific Literature | |||
5. | ALA1225074 | B | Inhibition of human huntingtin Q103 mutant expressed in rat PC12 cells assessed as decrease in cell death relative to control | 6 | cell-based format | Scientific Literature | |||
6. | ALA1225075 | B | Inhibition of huntingtin in Saccharomyces cerevisiae coexpressing exon 1 fragments with polyQ region Huntington disease (HD) model assessed as increase in cell viability | Saccharomyces cerevisiae | 29 | assay format | Scientific Literature | ||
7. | ALA1225076 | B | Inhibition of huntingtin mutant in Caenorhabditis elegans ASH neuronal cell Huntington disease model assessed as cell viability | Caenorhabditis elegans | 29 | cell-based format | Scientific Literature | ||
8. | ALA1225077 | F | Inhibition of medium spiny neuron degeneration in rat brain slice Huntington disease (HD) model after 4 days | Rattus norvegicus | 29 | tissue-based format | Scientific Literature | ||
9. | ALA1225080 | F | Inhibition of apoptosis in rat ST14A cells transfected with human htt gene assessed as inhibition of caspase 3 cleavage by Western blot method | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
10. | ALA1225081 | F | Inhibition of apoptosis in rat ST14A cells transfected with human htt gene assessed as inhibition of caspase 7 cleavage by Western blot method | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
11. | ALA4888485 | F | Primary screen in NF54 nanoGlo assay, in single point, at 2uM, 72h | Plasmodium falciparum | 147,432 | organism-based format | MMV Malaria HGL | ||
12. | ALA5225323 | B | Inhibition of HTT (unknown origin) | Homo sapiens | 6 | single protein format | Scientific Literature |