# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1226057 | B | Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells at 200 nM to 200 uM | Mus musculus | 2 | ALA1221358 | cell-based format | Scientific Literature | |
2. | ALA1226058 | A | Cytotoxicity against mouse RAW264.7 cells | Mus musculus | 2 | ALA1221358 | cell-based format | Scientific Literature | |
3. | ALA1226059 | B | Inhibition TLR4-mediated NO production in mouse RAW264.7 cells at 300 uM | Mus musculus | 1 | ALA1221358 | cell-based format | Scientific Literature | |
4. | ALA1226060 | B | Inhibition TLR3-mediated NO production in mouse RAW264.7 cells at 300 uM | Mus musculus | 1 | ALA1221358 | cell-based format | Scientific Literature | |
5. | ALA1226061 | B | Inhibition TLR2-mediated NO production in mouse RAW264.7 cells at 300 uM | Mus musculus | 1 | ALA1221358 | cell-based format | Scientific Literature | |
6. | ALA1226062 | B | Inhibition TLR6-mediated NO production in mouse RAW264.7 cells at 300 uM | Mus musculus | 1 | ALA1221358 | cell-based format | Scientific Literature | |
7. | ALA1226063 | B | Inhibition TLR7-mediated NO production in mouse RAW264.7 cells at 300 uM | Mus musculus | 1 | ALA1221358 | cell-based format | Scientific Literature | |
8. | ALA1226064 | B | Inhibition TLR1-mediated NO production in mouse RAW264.7 cells at 300 uM | Mus musculus | 1 | ALA1221358 | cell-based format | Scientific Literature | |
9. | ALA1226065 | B | Inhibition of TLR4 binding to MD4 | 2 | ALA1221358 | single protein format | Scientific Literature | ||
10. | ALA1827810 | B | Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrs | Mus musculus | 27 | ALA1821673 | cell-based format | Scientific Literature | |
11. | ALA1827811 | B | Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of IL-8 release preincubated for 5 to 10 mins | Homo sapiens | 2 | ALA1821673 | single protein format | Scientific Literature | |
12. | ALA1827812 | B | Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of TNFalpha release preincubated for 5 to 10 mins | Homo sapiens | 2 | ALA1821673 | single protein format | Scientific Literature | |
13. | ALA1827813 | B | Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of IL-6 release preincubated for 5 to 10 mins | Homo sapiens | 2 | ALA1821673 | single protein format | Scientific Literature | |
14. | ALA1827814 | B | Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of TNFalpha release at 250 uM preincubated for 5 to 10 mins | Homo sapiens | 1 | ALA1821673 | single protein format | Scientific Literature | |
15. | ALA1827815 | B | Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of IL-8 release at 500 uM preincubated for 5 to 10 mins | Homo sapiens | 2 | ALA1821673 | single protein format | Scientific Literature | |
16. | ALA1827816 | B | Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of TNFalpha release at 500 uM preincubated for 5 to 10 mins | Homo sapiens | 2 | ALA1821673 | single protein format | Scientific Literature | |
17. | ALA1827817 | B | Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of IL-6 release at 500 uM preincubated for 5 to 10 mins | Homo sapiens | 2 | ALA1821673 | single protein format | Scientific Literature | |
18. | ALA1827818 | B | Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of IL-6 release at 250 uM preincubated for 5 to 10 mins | Homo sapiens | 2 | ALA1821673 | single protein format | Scientific Literature | |
19. | ALA1827819 | B | Inhibition of LPS-induced TLR4 activation in human whole blood assessed as reduction in plasma IL-8 level at 250 uM preincubated for 5 to 10 mins | Homo sapiens | 1 | ALA1821673 | single protein format | Scientific Literature | |
20. | ALA1827820 | B | Inhibition of LPS-induced TLR4 activation in human whole blood assessed as reduction in plasma TNFalpha level at 250 uM preincubated for 5 to 10 mins | Homo sapiens | 1 | ALA1821673 | single protein format | Scientific Literature |