# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1225535 | Functional | Antioxidant activity assessed as DDPH radical scavenging activity | 30 | ALA1221328 | assay format | Scientific Literature | ||
2. | ALA4431996 | Functional | Antitrypanosomal activity against Trypanosoma brucei brucei Lister 427 bloodstream forms after 72 hrs by resazurin-based assay | Trypanosoma brucei brucei | 50 | ALA4431321 | organism-based format | Scientific Literature | |
3. | ALA4432001 | Binding | Inhibition of Leishmania mexicana DHFR at 50 uM using folic aid as substrate by spectrophotometric analysis | Leishmania mexicana | 8 | ALA4431321 | assay format | Scientific Literature | |
4. | ALA4432002 | Binding | Inhibition of Trypanosoma brucei DHFR at 50 uM using folic aid as substrate by spectrophotometric analysis | Trypanosoma brucei | 8 | ALA4431321 | assay format | Scientific Literature | |
5. | ALA4432003 | Binding | Inhibition of human DHFR at 50 uM using folic aid as substrate by spectrophotometric analysis | Homo sapiens | 7 | ALA4431321 | single protein format | Scientific Literature | |
6. | ALA4432004 | Binding | Inhibition of human thymidylate synthase at 50 uM using folic aid as substrate by spectrophotometric analysis | Homo sapiens | 8 | ALA4431321 | single protein format | Scientific Literature | |
7. | ALA4432006 | Toxicity | Mitochondrial toxicity in human 786-O cells incubated for 6 hrs by mitotracker red staining based-uptake method | Homo sapiens | 16 | ALA4431321 | cell-based format | Scientific Literature | |
8. | ALA4432007 | ADME | Cytotoxicity against human A549 cells at 100 uM after 48 hrs by cell titer glo assay | Homo sapiens | 16 | ALA4431321 | cell-based format | Scientific Literature | |
9. | ALA4432008 | ADME | Cytotoxicity against human WI38 cells at 100 uM after 48 hrs by cell titer glo assay | Homo sapiens | 16 | ALA4431321 | cell-based format | Scientific Literature | |
10. | ALA4432015 | Functional | Antitrypanosomal activity against Trypanosoma brucei brucei Lister 427 bloodstream forms at 10 uM after 72 hrs by resazurin-based assay | Trypanosoma brucei brucei | 13 | ALA4431321 | organism-based format | Scientific Literature | |
11. | ALA4432019 | ADME | Cytotoxicity against human THP1 cells after 72 hrs by MTT assay | Homo sapiens | 16 | ALA4431321 | cell-based format | Scientific Literature | |
12. | ALA4432020 | Toxicity | Selectivity index, ratio of CC50 for human THP1 cells to EC50 for Trypanosoma brucei brucei Lister 427 bloodstream forms | 16 | ALA4431321 | assay format | Scientific Literature | ||
13. | ALA4432023 | ADME | Inhibition of human microsomal CYP1A2 expressed in baculovirus infected BTI-TN-5B1-4 cells at 10 uM incubated for 30 mins by luciferase assay | Homo sapiens | 14 | ALA4431321 | cell-based format | Scientific Literature |