# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4828793 | B | Substrate activity at human OCT1 expressed in HEK293 cells assessed as increase in compound uptake by measuring Km incubated for 2 mins by LC-MS/MS analysis | Homo sapiens | 22 | ALA4828702 | cell-based format | Scientific Literature | |
2. | ALA4828794 | B | Substrate activity at human OCT1 expressed in HEK293 cells assessed as increase in compound uptake by measuring Vmax incubated for 2 mins by LC-MS/MS analysis | Homo sapiens | 22 | ALA4828702 | cell-based format | Scientific Literature | |
3. | ALA4828795 | B | Substrate activity at human OCT1 expressed in HEK293 cells assessed as increase in compound uptake by measuring intrinsic clearance incubated for 2 mins by LC-MS/MS analysis | Homo sapiens | 22 | ALA4828702 | cell-based format | Scientific Literature | |
4. | ALA4828796 | A | Ratio of drug uptake in human OCT1 expressing HEK293 cells at 2.5 uM to drug uptake in empty vector transfected human HEK293 cells at 2.5 uM | Homo sapiens | 22 | ALA4828702 | tissue-based format | Scientific Literature | |
5. | ALA5119563 | A | Substrate activity at human OCT3 overexpressed in HEK293 cells assessed as uptake ratio incubated for 2 mins by LC-MS/MS analysis | Homo sapiens | 15 | ALA5113524 | cell-based format | Scientific Literature | |
6. | ALA5119571 | B | Inhibition of human OCT3 mediated ASP+ uptake overexpressed in HEK293 cells at 20 uM incubated for 5 mins by HPLC-MS/MS analysis relative to control | Homo sapiens | 5 | ALA5113524 | cell-based format | Scientific Literature | |
7. | ALA5119575 | B | Inhibition of human OCT3 mediated methylscopolamine uptake overexpressed in HEK293 cells at 20 uM incubated for 5 mins by HPLC-MS/MS analysis relative to control | Homo sapiens | 5 | ALA5113524 | cell-based format | Scientific Literature |