# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA660894 | B | Inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I from rat liver mitochondria | Rattus norvegicus | 13 | ALA1145104 | mitochondrion format | Scientific Literature | |
2. | ALA874517 | B | In vitro inhibition of [14C]palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondria | Rattus norvegicus | 13 | ALA1145104 | mitochondrion format | Scientific Literature | |
3. | ALA2216987 | F | Reduction in glucose level in db/db mouse at 80 mg/kgl/day, po for 12 days | Mus musculus | 1 | ALA2216752 | organism-based format | Scientific Literature | |
4. | ALA2216989 | F | Inhibition of ketogenesis in fasted po dosed cynomolgus monkey | Macaca fascicularis | 1 | ALA2216752 | organism-based format | Scientific Literature | |
5. | ALA2216991 | F | Reduction in glucose production in Sprague-Dawley rat at 5 to 25 pmol, icv administered as one or two single doses | Rattus norvegicus | 1 | ALA2216752 | organism-based format | Scientific Literature | |
6. | ALA2216992 | F | Reduction in blood glucose level in db/db mouse at 50 mg/kg, po bid for 45 days | Mus musculus | 1 | ALA2216752 | organism-based format | Scientific Literature | |
7. | ALA2216993 | F | Reduction in BHB level in po dosed 24 hrs fasted rat measured up to 12 hrs post dose | Rattus norvegicus | 1 | ALA2216752 | organism-based format | Scientific Literature | |
8. | ALA2216994 | F | Increase in circulating FFA level in db/db mouse at 50 mg/kg, po bid for 45 days | Mus musculus | 1 | ALA2216752 | organism-based format | Scientific Literature | |
9. | ALA2216995 | F | Increase in liver TG level in db/db mouse at 50 mg/kg, po bid for 45 days | Mus musculus | 1 | ALA2216752 | organism-based format | Scientific Literature | |
10. | ALA2216996 | F | Reduction in water consumption in db/db mouse at 50 mg/kg, po bid for 45 days | Mus musculus | 1 | ALA2216752 | organism-based format | Scientific Literature | |
11. | ALA2216997 | F | Reduction in serum fructosamine level in db/db mouse at 50 mg/kg, po bid for 45 days | Mus musculus | 1 | ALA2216752 | organism-based format | Scientific Literature | |
12. | ALA2216998 | F | Reduction in liver glycogen level in db/db mouse at 50 mg/kg, po bid for 45 days | Mus musculus | 1 | ALA2216752 | organism-based format | Scientific Literature | |
13. | ALA2216999 | F | Reduction in serum glucose in db/db mouse at 50 mg/kg, po bid for 45 days | Mus musculus | 1 | ALA2216752 | organism-based format | Scientific Literature | |
14. | ALA2217013 | B | Inhibition of carnitine palmitoyltransferase in rat heart mitochondria assessed as conversion of [14C]palmitic acid to [14C]palmitoylcarnitine by radiometric assay | Rattus norvegicus | 6 | ALA2216752 | mitochondrion format | Scientific Literature | |
15. | ALA2217014 | B | Inhibition of carnitine palmitoyltransferase in rat liver mitochondria assessed as conversion of [14C]palmitic acid to [14C]palmitoylcarnitine by radiometric assay | Rattus norvegicus | 6 | ALA2216752 | mitochondrion format | Scientific Literature | |
16. | ALA2217023 | B | Inhibition of rat FAO | Rattus norvegicus | 15 | ALA2216752 | assay format | Scientific Literature | |
17. | ALA2217024 | F | Cytotoxicity in human KB cells | Homo sapiens | 23 | ALA2216752 | cell-based format | Scientific Literature | |
18. | ALA2217025 | B | Inhibition of human FAO | Homo sapiens | 15 | ALA2216752 | assay format | Scientific Literature | |
19. | ALA2217026 | B | Inhibition of human CPT2 | Homo sapiens | 14 | ALA2216752 | single protein format | Scientific Literature | |
20. | ALA2217027 | B | Maximal inhibition of rat CPT1A | Rattus norvegicus | 7 | ALA2216752 | single protein format | Scientific Literature |