1. ALA2318056 Binding Inhibition of HIV-1 protease I54M mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition measured for 5 mins by fluorescence assay Human immunodeficiency virus 1 1 ALA2311291 assay format Scientific Literature 2. ALA2318057 Binding Inhibition of HIV-1 protease I50V mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition measured for 5 mins by fluorescence assay Human immunodeficiency virus 1 1 ALA2311291 assay format Scientific Literature 3. ALA2318301 Binding Inhibition of HIV-1 protease D30N mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition measured for 5 mins by fluorescence assay Human immunodeficiency virus 1 1 ALA2311291 assay format Scientific Literature 4. ALA2318302 Binding Inhibition of HIV-1 protease R8Q mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition measured for 5 mins by fluorescence assay Human immunodeficiency virus 1 1 ALA2311291 assay format Scientific Literature 5. ALA2318303 Binding Inhibition of HIV-1 wildtype protease using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition measured for 5 mins by fluorescence assay Human immunodeficiency virus 1 1 ALA2311291 single protein format Scientific Literature 6. ALA2318304 Binding Ratio of Ki for HIV-1 protease V82A mutant to Ki for HIV-1 wildtype protease Human immunodeficiency virus 1 1 ALA2311291 assay format Scientific Literature 7. ALA2318305 Binding Ratio of Ki for HIV-1protease I54M mutant to Ki for HIV-1 wildtype protease Human immunodeficiency virus 1 1 ALA2311291 assay format Scientific Literature 8. ALA2318306 Binding Ratio of Ki for HIV-1 protease D30N mutant to Ki for HIV-1 wildtype protease Human immunodeficiency virus 1 1 ALA2311291 assay format Scientific Literature 9. ALA2318307 Binding Ratio of Ki for HIV-1 protease I50V mutant to Ki for HIV-1 wildtype protease Human immunodeficiency virus 1 1 ALA2311291 assay format Scientific Literature 10. ALA2318308 Binding Inhibition of HIV-1 protease V82A mutant using Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 as substrate incubated for 5 mins prior to substrate addition measured for 5 mins by fluorescence assay Human immunodeficiency virus 1 1 ALA2311291 assay format Scientific Literature 11. ALA2318309 Binding Ratio of Ki for HIV-1 protease R8Q mutant to Ki for HIV-1 wildtype protease Human immunodeficiency virus 1 1 ALA2311291 assay format Scientific Literature 12. ALA2352955 Binding Inhibition of HIV1 protease dimerization transfected in COS7 cells relative to darunavir Human immunodeficiency virus 1 1 ALA2346554 cell-based format Scientific Literature 13. ALA2352956 Binding Ratio of amprenavir dissociation constant K to compound dissociation constant K for HIV1 protease Q7K, L10F, I13V, I15V, D30V, V32I, L33F, E35D, M36I, S37N, I47V, I54L, Q58E, I62V, L63P, A71V, I84V, N88D, L89T, L90M mutant Human immunodeficiency virus 1 1 ALA2346554 assay format Scientific Literature 14. ALA2353179 Binding Inhibition of transferrin receptor-fused HIV1 protease Q7K, L10F, I13V, I15V, D30V, V32I, L33F, E35D, M36I, S37N, I47V, I54L, Q58E, I62V, L63P, A71V, I84V, N88D, L89T, L90M mutant autoprocessing expressed in Escherichia coli up to 100 uM by SDS-PAGE analysis Human immunodeficiency virus 1 2 ALA2346554 assay format Scientific Literature 15. ALA2353181 Binding Binding affinity to HIV1 protease Q7K, L10F, I13V, I15V, D30V, V32I, L33F, E35D, M36I, S37N, I47V, I54L, Q58E, I62V, L63P, A71V, I84V, N88D, L89T, L90M mutant expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant by isothermal titration calorimetric analysis Human immunodeficiency virus 1 4 ALA2346554 assay format Scientific Literature 16. ALA2353182 Binding Binding affinity to HIV1 protease Q7K, L10F, I13V, I15V, D30V, V32I, L33F, E35D, M36I, S37N, I47V, I54L, Q58E, I62V, L63P, A71V, I84V, N88D, L89T, L90M mutant expressed in Escherichia coli BL21 (DE3) assessed as association constant by isothermal titration calorimetric analysis Human immunodeficiency virus 1 4 ALA2346554 assay format Scientific Literature 17. ALA2428516 Binding Inhibition of HIV1 protease Human immunodeficiency virus 1 1 ALA2424573 single protein format Scientific Literature 18. ALA2428517 Functional Antiviral activity against HIV1 LAV Human immunodeficiency virus 1 1 ALA2424573 organism-based format Scientific Literature 19. ALA5247084 Binding Inhibition of HIV-1 protease Human immunodeficiency virus 1 5 ALA5244275 single protein format Scientific Literature 20. ALA5252950 Binding Binding affinity to HIV1 protease assessed as inhibition constant Human immunodeficiency virus 1 20 ALA5252512 single protein format Scientific Literature