# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1692976 | B | Inhibition of human LDH-A using pyruvate as substrate and NADH as cofactor at 125 uM after 5 mins by calorimetric assay relative to control | Homo sapiens | 13 | single protein format | Scientific Literature | ||
2. | ALA5236847 | B | Inhibition of recombinant Plasmodium falciparum LDH | Plasmodium falciparum | 6 | single protein format | Scientific Literature | ||
3. | ALA5236848 | B | Inhibition of human recombinant LDH | Homo sapiens | 6 | assay format | Scientific Literature | ||
4. | ALA5236851 | B | Binding affinity to Plasmodium falciparum LDH assessed as inhibitory constant | Plasmodium falciparum | 3 | assay format | Scientific Literature | ||
5. | ALA5236852 | F | Antimalarial activity against drug sensitive Plasmodium falciparum 3D7 | Plasmodium falciparum | 3 | organism-based format | Scientific Literature | ||
6. | ALA5236856 | F | Antimalarial activity against Plasmodium falciparum assessed as parasitic reduction at 100 mg/kg relative to control | Plasmodium falciparum | 2 | organism-based format | Scientific Literature | ||
7. | ALA5236857 | F | Antimalarial activity against Plasmodium falciparum assessed as parasitic reduction at 10 mg/kg of chloroquine relative to control | Plasmodium falciparum | 2 | organism-based format | Scientific Literature | ||
8. | ALA5236858 | A | Cmax in mouse at 100 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
9. | ALA5236859 | A | Cmax in mouse at 100 mg/kg, ip | Mus musculus | 2 | organism-based format | Scientific Literature | ||
10. | ALA5236860 | A | Half life in mouse at 10 mg/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
11. | ALA5236861 | A | Half life in mouse at 10 mg/kg, ip | Mus musculus | 2 | organism-based format | Scientific Literature |