# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1692976 | B | Inhibition of human LDH-A using pyruvate as substrate and NADH as cofactor at 125 uM after 5 mins by calorimetric assay relative to control | Homo sapiens | 13 | ALA1687923 | single protein format | Scientific Literature | |
2. | ALA2060669 | B | Binding affinity to 6-His-tagged human LDHA (2 to 322 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells by NMR analysis in presence of NAD+ | Homo sapiens | 2 | ALA2057123 | cell-based format | Scientific Literature | |
3. | ALA2060670 | B | Binding affinity to 6-His-tagged human LDHA (2 to 322 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells by SPR analysis | Homo sapiens | 30 | ALA2057123 | cell-based format | Scientific Literature | |
4. | ALA2060671 | B | Inhibition of full length human recombinant LDHA expressed in Escherichia coli BL21 (DE3) cells after 10 mins by spectrophotometric analysis | Homo sapiens | 33 | ALA2057123 | cell-based format | Scientific Literature | |
5. | ALA2060672 | B | Inhibition of human recombinant LDHB (2 to 334 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells after 10 mins by spectrophotometric analysis | Homo sapiens | 8 | ALA2057123 | cell-based format | Scientific Literature | |
6. | ALA5236847 | B | Inhibition of recombinant Plasmodium falciparum LDH | Plasmodium falciparum | 6 | ALA5236544 | single protein format | Scientific Literature | |
7. | ALA5236848 | B | Inhibition of human recombinant LDH | Homo sapiens | 6 | ALA5236544 | assay format | Scientific Literature | |
8. | ALA5236851 | B | Binding affinity to Plasmodium falciparum LDH assessed as inhibitory constant | Plasmodium falciparum | 3 | ALA5236544 | assay format | Scientific Literature | |
9. | ALA5236852 | F | Antimalarial activity against drug sensitive Plasmodium falciparum 3D7 | Plasmodium falciparum | 3 | ALA5236544 | organism-based format | Scientific Literature | |
10. | ALA5236853 | F | Antimalarial activity against drug resistant Plasmodium falciparum KI | Plasmodium falciparum | 2 | ALA5236544 | organism-based format | Scientific Literature |