# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4418847 | Binding | Inhibition of His-tagged human recombinant SHMT2 expressed in Escherichia coli BLR(DE3) assessed as reduction in NADPH level using L-serine, THF and NADP+ at 6.5 or 26.5 uM incubated for 5 mins by SHMT2-MTHFD coupled reaction based fluorescence assay relative to control | Homo sapiens | 46 | ALA4418497 | assay format | Patent Bioactivity Data | |
2. | ALA2166270 | Binding | Inhibition of electric eel AChE at 2 mg/ml by Ellman's method | Electrophorus electricus | 500 | ALA2163249 | single protein format | Scientific Literature | |
3. | ALA2166271 | Binding | Inhibition of horse BChE at 2 mg/ml by Ellman's method | Equus caballus | 500 | ALA2163249 | single protein format | Scientific Literature | |
4. | ALA2343414 | Binding | Induction of beta hexosaminidase activity in fibroblasts derived from TSD patient at 250 uM after 4 to 6 days by fluorescence assay relative to control | Homo sapiens | 4 | ALA2331344 | assay format | Scientific Literature | |
5. | ALA2343418 | Binding | Inhibition of jack bean beta hexosaminidase | Canavalia ensiformis | 3 | ALA2331344 | assay format | Scientific Literature | |
6. | ALA4135472 | ADME | Cytotoxicity against human HL cells assessed as cell viability at 50 uM after 72 hrs by resazurin dye based fluorescence assay relative to control | Homo sapiens | 53 | ALA4130515 | cell-based format | Scientific Literature | |
7. | ALA4135473 | Functional | Antichlamydial activity against Chlamydia pneumoniae K7 infected in HL cells assessed as chlamydial inhibition at 50 uM after 70 hrs by fluorescent microscopic analysis | Chlamydia pneumoniae | 26 | ALA4130515 | organism-based format | Scientific Literature | |
8. | ALA4135474 | Functional | Antichlamydial activity against Chlamydia pneumoniae K7 infected in HL cells after 70 hrs by fluorescent microscopic analysis | Chlamydia pneumoniae | 7 | ALA4130515 | organism-based format | Scientific Literature |