# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1776260 | B | Inhibition of EthR in Mycobacterium tuberculosis H37Rv expressing GFP infected in mouse RAW264.7 cells assessed as concentration required to ethionamide-induced 50% inhibition of bacterial growth after 5 days by microscopic analysis | Mycobacterium tuberculosis H37Rv | 58 | cell-based format | Scientific Literature | ||
2. | ALA1776262 | B | Inhibition of Mycobacterium tuberculosis EthR interaction to ethA promoter after 5 mins by surface plasmon resonance assay | Mycobacterium tuberculosis | 8 | single protein format | Scientific Literature | ||
3. | ALA1776264 | P | Solubility of the compound at pH 7.4 after 24 hrs | 5 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA1776265 | A | Half life in CD1 mouse liver microsomes by LC-MS-MS analysis | Mus musculus | 5 | microsome format | Scientific Literature | ||
5. | ALA1776266 | A | Intrinsic clearance in CD1 mouse liver microsomes by LC-MS-MS analysis | Mus musculus | 5 | microsome format | Scientific Literature |