# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3625041 | Functional | Antiviral activity against HIV1 infected in human MT4 cells expressing GFP incubated for 48 to 72 hrs in absence of 50% normal human serum by multiple round viral replication kinetics assay | Human immunodeficiency virus 1 | 10 | ALA3621084 | organism-based format | Scientific Literature | |
2. | ALA3625042 | Functional | Antiviral activity against HIV1 infected in human MT4 cells expressing GFP incubated for 48 to 72 hrs in presence of 50% normal human serum by multiple round viral replication kinetics assay | Human immunodeficiency virus 1 | 5 | ALA3621084 | organism-based format | Scientific Literature | |
3. | ALA3625159 | Functional | Resistance index, ratio of IC50 for antiviral activity against HIV1 expressing integrase E92Q mutant to IC50 for antiviral activity against HIV1 expressing wild type integrase | Human immunodeficiency virus 1 | 5 | ALA3621084 | organism-based format | Scientific Literature | |
4. | ALA3625160 | Functional | Resistance index, ratio of IC50 for antiviral activity against HIV1 expressing integrase Y143R mutant to IC50 for antiviral activity against HIV1 expressing wild type integrase | Human immunodeficiency virus 1 | 5 | ALA3621084 | organism-based format | Scientific Literature | |
5. | ALA3625161 | Functional | Resistance index, ratio of IC50 for antiviral activity against HIV1 expressing integrase Q148R mutant to IC50 for antiviral activity against HIV1 expressing wild type integrase | Human immunodeficiency virus 1 | 5 | ALA3621084 | organism-based format | Scientific Literature | |
6. | ALA3625162 | Functional | Resistance index, ratio of IC50 for antiviral activity against HIV1 expressing integrase Q148K mutant to IC50 for antiviral activity against HIV1 expressing wild type integrase | Human immunodeficiency virus 1 | 5 | ALA3621084 | organism-based format | Scientific Literature | |
7. | ALA3625163 | Functional | Resistance index, ratio of IC50 for antiviral activity against HIV1 expressing integrase N155H mutant to IC50 for antiviral activity against HIV1 expressing wild type integrase | Human immunodeficiency virus 1 | 5 | ALA3621084 | organism-based format | Scientific Literature | |
8. | ALA3625164 | ADME | Plasma clearance in rat | Rattus norvegicus | 1 | ALA3621084 | organism-based format | Scientific Literature | |
9. | ALA3625165 | ADME | Oral bioavailability in rat | Rattus norvegicus | 1 | ALA3621084 | organism-based format | Scientific Literature | |
10. | ALA3625166 | ADME | Plasma clearance in dog | Canis lupus familiaris | 1 | ALA3621084 | organism-based format | Scientific Literature | |
11. | ALA3625844 | ADME | Oral bioavailability in dog | Canis lupus familiaris | 1 | ALA3621084 | organism-based format | Scientific Literature | |
12. | ALA3625845 | ADME | Intrinsic clearance in human hepatocytes at 1 uM by LC-MS/MS method | Homo sapiens | 1 | ALA3621084 | cell-based format | Scientific Literature | |
13. | ALA5237336 | Functional | Antiviral activity against HIV-1 harboring integrase Q148R mutant | Human immunodeficiency virus | 6 | ALA5236553 | organism-based format | Scientific Literature | |
14. | ALA5237338 | Functional | Antiviral activity against HIV-1 harboring integrase N155H mutant | Human immunodeficiency virus | 6 | ALA5236553 | organism-based format | Scientific Literature | |
15. | ALA5237339 | Functional | Antiviral activity against HIV-1 harboring integrase E92Q mutant | Human immunodeficiency virus | 4 | ALA5236553 | organism-based format | Scientific Literature | |
16. | ALA5237340 | Functional | Antiviral activity against HIV-1 harboring integrase Y143R mutant | Human immunodeficiency virus | 4 | ALA5236553 | organism-based format | Scientific Literature | |
17. | ALA5237341 | Functional | Antiviral activity against HIV-1 harboring integrase Q148K mutant | Human immunodeficiency virus | 4 | ALA5236553 | organism-based format | Scientific Literature | |
18. | ALA5237342 | ADME | Clearance in rat plasma | Rattus norvegicus | 1 | ALA5236553 | cell-free format | Scientific Literature | |
19. | ALA5237343 | ADME | Clearance in dog plasma | Canis lupus familiaris | 1 | ALA5236553 | cell-free format | Scientific Literature |