| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3856337 | B | Inhibition of recombinant human GST-tagged SIRT1 overexpressed in Escherichia coli DH5alpha assessed as deacetylation activity using [3H]-MPSDKTIGG as substrate measured after overnight incubation by liquid scintillation counting method | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 2. | ALA3856338 | B | Inhibition of recombinant human GST-tagged SIRT2 overexpressed in Escherichia coli DH5alpha assessed as deacetylation activity using [3H]-MPSDKTIGG as substrate measured after overnight incubation by liquid scintillation counting method | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 3. | ALA3857901 | B | Inhibition of glutamate transporter (unknown origin) assessed as suppression of synaptosomal uptake of L-glutamate | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 4. | ALA3857902 | B | Inhibition of GABA transporter (unknown origin) assessed as suppression of synaptosomal uptake of GABA | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 5. | ALA3857903 | B | Inhibition of serotonin transporter (unknown origin) assessed as suppression of synaptosomal uptake of serotonin | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 6. | ALA3857904 | B | Inhibition of norepinephrine transporter (unknown origin) assessed as suppression of synaptosomal uptake of norepinephrine | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA3857905 | B | Inhibition of dopamine transporter (unknown origin) assessed as suppression of synaptosomal uptake of dopamine | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 8. | ALA3859514 | B | Inhibition of N-terminal His6-tagged recombinant human SIRT1 expressed in Escherichia coli at 32 uM using RHKK(Ac)W-NH2 as substrate by UV detection-based HPLC method | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 9. | ALA3859515 | B | Inhibition of 250 nM N-terminal His6-tagged recombinant human SIRT1 expressed in Escherichia coli at 100 uM using RHKK(Ac)W-NH2 as substrate after 5 to 10 mins by UV detection-based HPLC method | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 10. | ALA3859516 | B | Inhibition of 50 nM N-terminal His6-tagged recombinant human SIRT1 expressed in Escherichia coli at 100 uM using RHKK(Ac)W-NH2 as substrate after 30 mins by UV detection-based HPLC method | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 11. | ALA3859518 | B | Activation of 50 nM N-terminal His6-tagged recombinant human SIRT1 expressed in Escherichia coli at 100 uM using RHKK(Ac)W-NH2 as substrate after 30 mins in presence of 0.01% TX-100 by UV detection-based HPLC method relative to control | Homo sapiens | 3 | assay format | Scientific Literature | ||
| 12. | ALA4152545 | B | Inhibition of mPGES1 (unknown origin) assessed as reduction in conversion of PGH to PGE2 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA5246965 | A | Induction of CYP3A in human assessed as reduction in midazolam AUC | Homo sapiens | 9 | protein format | Scientific Literature | ||
| 14. | ALA5246986 | B | Activation of human PXR | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 15. | ALA5246994 | B | Activation of PXR (unknown origin) relative to control | Homo sapiens | 12 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!