# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1244670 | B | Inhibition of Myc-tagged human Dusp6 expressed in TPA-induced human HeLa cells assessed as decrease in dephosphorylation of pERK measured at 100 uM by immunostaining | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA1244671 | B | Inhibition of Myc-tagged human Dusp1 expressed in TPA-induced human HeLa cells assessed as decrease in dephosphorylation of pERK measured at 100 uM by immunostaining | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4420888 | B | Inhibition of Dusp6 in (Tg(Dusp6:d2EGFP)pt6) transgenic Zebrafish assessed as activation of FGF signaling at 20 uM by d2EGFP fluorescence based assay | Danio rerio | 2 | single protein format | Patent Bioactivity Data | ||
4. | ALA4420895 | B | Inhibition of Myc-tagged human Dusp6 expressed in TPA-stimulated human HeLa cells assessed as suppression of Dusp6-induced reduction in ERK phosphorylation at 0.5 to 2 uM by immunostaining based assay | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
5. | ALA4420896 | B | Inhibition of Myc-tagged human Dusp1 expressed in TPA-stimulated human HeLa cells assessed as suppression of Dusp6-induced reduction in ERK phosphorylation at 0.5 to 2 uM by immunostaining based assay | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
6. | ALA4420897 | B | Inhibition of recombinant His-tagged Dusp6 (unknown origin) assessed as suppression of pBRK2 dephosphorylation at 100 uM incubated for 60 mins by immunoblotting | Homo sapiens | 2 | single protein format | Patent Bioactivity Data | ||
7. | ALA4420918 | B | Inhibition of Dusp6 in (Tg(Dusp6:d2EGFP)pt6) transgenic Zebrafish assessed as activation of FGF signaling at 20 uM treated at 24 hours post fertilization and measured after 6 hrs post dose by d2EGFP fluorescence based assay relative to BCI | Danio rerio | 18 | single protein format | Patent Bioactivity Data |